Amyloid β/A4 Protein Precursor (740-770) (C31)
Bachem
polyclonal
IgG
Rabbit
(purified antiserum)
-
-
immunogen = amino acids 640-670 from Amyloid precursor protein
detects Amyloid β/A4 Protein Precursor
-
Amyloid β/A4 Protein Precursor (740-770) (C31)
Bachem
polyclonal
IgG
Rabbit
(purified antiserum, diluted)
-
-
immunogen = amino acids 640-670 from Amyloid precursor protein
detects Amyloid β/A4 Protein Precursor
-
Amyloid β/A4 Protein Precursor (740-770) (C31)
Bachem
kit
IgG
Rabbit
-
-
-
detects Amyloid β/A4 Protein Precursor
-
APP
Biodesign Meridian LifeScience
polyclonal
Goat
(neat liquid azide)
-
Human
immunogen = synthetic peptide (G Y E N P T Y K F F E Q M Q N) aa. 681-695, C-terminal
recognizes aa. 681-695 of human APP
-
APP
Biodesign Meridian LifeScience
polyclonal
Goat
(neat liquid azide)
-
Human
immunogen = synthetic peptide (R G R T S S K E L A) aa. 339-348 (C-terminal) of human APP, frameshift mutant
aa. 339-348 of human APP frameshift mutant
-
APP frameshift mutant
Biodesign Meridian LifeScience
polyclonal
Goat
(neat liquid azide)
-
Human
immunogen = synthetic peptide (R G R T S S K E L A) aa. 339-348 (C-terminal) of human APP, frameshift mutant
aa. 339-348 of human APP frameshift mutant
-
APP
Biodesign Meridian LifeScience
polyclonal
Goat
(neat liquid azide)
-
Human
immunogen = synthetic peptide (H M N V Q N G K W D S D P S G T K T CI) aa. 44-63, N-terminal
aa. 44-63 of human APP
-
APP
Biodesign Meridian LifeScience
polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = aa. 653-662 of human APP A4 or aa. 1-10 of the Aβ peptide generated by β- and γ-secretase cleavages
recognizes aa. 653-662 of APP and aa. 1-10 of amyloidβ
-
APP
Biodesign Meridian LifeScience
polyclonal
Rabbit
(liquid, PBS, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = aa. 737-751, C-terminal of human APP A4 or 85 to 99 of the C99 fragment generated by β-secretase cleavage
detects APP and C99 fragment
-
APP phos Thr668
Biosource Invitrogen
polyclonal
Rabbit
(liquid, PBS, BSA, affinity purified, unconjugated, glycerol)
-
Frog, Human, Rat
immunogen = synthetic phosphopeptide derived from the region of human APP that contains threonine 668 (corresp. to APP695)
APP
-
APP (mAbP2-1)
Biosource Invitrogen
monoclonal
IgG1
Mouse
(liquid, PBS, protein G purified, no preservative, unconjugated)
-
Human, Monkey
immunogen = full length native secreted APP (protease nexin-II); epitope = aa 104-118
APP
-
AβPP
Biosource Invitrogen
monoclonal
Mouse
(liquid, unconjugated)
-
Human
-
APP
-
APP
Biosource Invitrogen
kit
(one strip-well plate, liquid stable chromogen and stop reagents)
-
Human
APP; sensitivity
-
APP phos Thr 668
Biosource Invitrogen
polyclonal
Rabbit
(liquid, Ig, PBS, BSA, glycerol, azide, affinity purified, unconj)
-
Human
immunogen = synthetic phospho-peptide derived from the region of human APP that contains threonine 668 (corresp.to the APP695 isoform)
APP phosphorylated at threonine 668
-
APP (J4H9)
Biotrend
monoclonal
IgG2b , κ
Mouse
(Ig fract)
-
Human
-
APP
Biotrend
polyclonal
Chicken
(antiserum, unpurified)
-
Human
immunogen = 15aa peptide of human APP770
APP
-
APP
Biotrend
polyclonal
Goat
(neat serum, azide)
-
Human
immunogen = synthetic 20-aa peptide near the extracellular, N-terminus (44-63 aa) of human APP695
all major APP isoforms (APP695, APP751, and APP770)
-
APP
Biotrend
monoclonal
IgG1
Mouse
(liquid, affinity purified)
-
Human, Mouse, Rat
immunogen = 21aa peptide of human APP695, N-terminal
APP
-
APP
Biotrend
polyclonal
Goat
(antiserum, unpurified)
-
Human
immunogen = 15aa peptide of human APP695, C-terminal
APP isoforms (APP695, APP751, and APP770)
-
APP
Biotrend
polyclonal
IgG
Goat
(liquid, Ig fract, PBS, purified, azide)
-
Human
immunogen = synthetic peptide corresp. to aa 44-63 of the N-terminus of APP
APP residues 44-63 on the N-terminus
-
APP
Biotrend
polyclonal
IgG
Goat
(liquid, Ig fract, PBS, azide, purified)
-
Human
immunogen = synthetic human corresp. to aa 681-695 (G Y E N P T Y K F F E Q M Q N) of human APP695
residues 681-695 on C-terminus of APP
-
APP frameshift mutant
Biotrend
polyclonal
IgG
Goat
(liquid, Ig fract, PBS, purified, azide)
-
Human
immunogen = synthetic peptide (R G R T S S K E L A) corresp. to aa229-348 of the C-terminus of human APP frameshift mutant (APPFM)
residues 339-348 of APP, Frameshift mutant
-
APP (3E9)
Biotrend
monoclonal
IgG1
Mouse
(lyophilized, PBS, sucrose, protein A purified)
-
Human, Mouse
immunogen = 21 aa synthetic peptide (L E V P T D G N A G L L A E P Q I A M F C) based on the human APP695 (residues 18-38)
APP
-
APP
Biotrend
polyclonal
IgG1
Rabbit
(liquid, PBS, azide)
-
Human, Mouse, Rat
immunogen = human APP synthetic peptide corresp. to aa residues 737-751 of the full length protein or to residues 85-99 in the human C99 fragment generated by γ-secretase cleavage.
APP (~105kDa) and C99 fragment (35kDa)
-
APP
Biotrend
polyclonal
IgG1
Rabbit
(liquid, PBS, azide)
-
Human, Mouse, Rat
immunogen = human APP synthetic peptide corresp. to aa residues 737-751 of the full length protein or to residues 85-99 in the human C99 fragment generated by γ-secretase cleavage.
APP (~105kDa) and C99 fragment (35kDa)
-
APP
Biotrend
polyclonal
Rabbit
(liquid, Ig fract, purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to N-terminal of human APP
recognizes amyloid precursor protein (β-APP770), amyloid precursor protein (APP) and APP-like proteins
-
APP binding family B, 1
Biotrend
polyclonal
Goat
(liquid, Ig fract, TBS, azide, BSA, affinity purified)
-
Human, Mouse
immunogen = peptide seq. C-G S L K P K P L G A H T P, from the C-terminus of the protein seq.
recognizes both isoforms (NP_001155.1 and NP_663722.1
-
APP binding family A, 1
Biotrend
polyclonal
Goat
(liquid, Ig fract, TBS, azide, BSA, affinity purified)
-
Human, Mouse, Rat
immunogen = peptide seq. C-E A S H P S Q D G K R Q Y K, from the internal region of the protein seq. according to NP_001154.2
APBA1/MINT1
-
APLP1, C-term
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(undiluted serum, liquid, no preserve)
-
Human, Mouse, Rat
immunogen = synthetic peptide (N P T Y R F L E E R P) aa 643-653 at the C-terminus of APLP1, coupled to KLH
APLP1; not APP or APLP2
-
APLP2, C-term
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(undiluted serum, liquid, no preserve)
-
Human, Mouse, Rat
immunogen = synthetic peptide (N P T Y K Y L E Q M Q I) aa 752-763 at the C-terminus of mouse APLP2, coupled to KLH
APLP2; not APP or APLP1
-
APLP2, full length
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(undiluted serum, liquid, no preserve)
-
Human, Mouse, Rat
immunogen = full-length mouse APLP2
APLP2; not APP or APLP1
-
APP-CT20 /0443
Calbiochem EMD Biosciences
polyclonal
IgG
Rabbit
(liquid, undiluted serum, no preserve)
-
Human
immunogen = synthetic peptide (K M Q Q N G Y E N P T Y K F F E Q M Q N) at C-terminal region (aa 751-770) of human APP, conj. to KLH
detects C-terminal products CTFα (~9 kDa), CTFβ (~11 kDa) and CTFγ (~6 kDa) and full length APP
-
APP (3E9)
Calbiochem EMD Biosciences
monoclonal
IgG1
Mouse
(lyophilized, PBS, sucrose, azide, protein A purified)
-
Human
immunogen = synthetic peptide (L E V P T D G N A G L L A E P Q I A M F C) corresp. to aa 18-38 of human APP695
APP695 (~110-135 kDa)
-
APP Phos Thr668
Cell Signaling
polyclonal
Rabbit
(HEPES, NaCl, BSA, glycerol, Protein-A)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to residues surrounding Thr668 of human APP695, conj. to KLH
APP A4 when phosphorylated at Thr668 (position corresponding to APP695 isoform)
-
APP Phos Thr668
Cell Signaling
polyclonal
Rabbit
(HEPES, NaCl, BSA, glycerol, Protein-A)
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to residues surrounding Thr668 of human APP695, conj. to KLH
detects different isoforms of endogenous amyloid β (A4) precursor protein only when phosphorylated at Thr668 (position corresponding to APP695 isoform)
-
APP, KPI domain (4.1)
Chemicon and Upstate are Millipore
monoclonal
IgG1
Mouse
(liquid, PBS, purified)
-
Human
immunogen = purified recombinant KPI domain of APP
APP, KPI domain (native and recombinant protein); partially inhibits protease inhibitory protein
-
APP, KPI domain
Chemicon and Upstate are Millipore
polyclonal
Rabbit
(serum, liquid, azide)
-
Human
immunogen = synthetic peptide corresp. to a part of KPI domain in soluble APP
soluble APP, KPI domain
-
APP (D3B10)
BioLegend
monoclonal
IgG1
Mouse
(purified, ascites, PBS, no preservatives or carrier proteins)
-
Human
Epitope lies within amino acids 61-77 of amyloid precursor protein
APP
Available from BioLegend
APP (1G6)
BioLegend
monoclonal
IgG1
Mouse
(purified, PBS, no preservatives or carrier proteins, biotinylated)
-
Human
Epitope lies within amino acids 573-596 of amyloid precursor protein
APP
Available from BioLegend
APP (LN27)
BioLegend
monoclonal
IgG1
Mouse
(liquid, protein G purified, no preservative)
-
-
-
recognizes all three known forms of APP (amyloid precursor protein), β-APP695, β-APP751 and β-APP770
Available from BioLegend
APPβ
None
kit
IgG1
Rabbit
-
Human, Mouse, Rat
immunogen = synthetic peptide corresp. to aa 573-596 of APP (amyloid precursor protein)
specific for the β isoform of sAPP (soluble amyloid precursor protein). It has negligible cross reactivity with β amyloid 40, 42, or sAPPα
Discontinued
APP (40.10)
Fitzgerald
monoclonal
IgM
Mouse
(lyophilized, supernatant, azide, affinity purified)
-
Human
immunogen = prokaryotic rh fusion protein corresp. to the extracellular portion of APP between the Kunitz protease inhibitor domain and the beta-amyloid region
APP
-
APP
Fitzgerald
polyclonal
Goat
-
-
immunogen = C-terminus of APP
APP C-terminus
-
APP frameshift mutant
Fitzgerald
polyclonal
Goat
-
-
immunogen = APP frameshift mutatant C-terminus
APP C-terminus, frameshift mutant
-
APP
Fitzgerald
polyclonal
Goat
-
-
immunogen = APP N-terminus
APP N-terminus,
-
APP, Frameshift mutant
Fitzgerald
polyclonal
Goat
(neat serum, no preservative)
-
Human
immunogen = synthetic peptide corresp. to aa 339-348 of the C-terminal APP frameshift mutant
C-terminus aa 339-348 of human APPFM
-
APP N-term
Fitzgerald
polyclonal
Goat
(liquid, neat serum, azide)
-
Human
immunogen = synthetic peptide equivalent to aa 44-63 of the N-terminus of human APP
APP N-terminus, residues 44-63
-
APP C-term
Fitzgerald
polyclonal
Goat
(neat serum, no preservative)
-
Human
immunogen = synthetic peptide corresp. to aa 681-695 on the C-terminal of APP
C-terminus aa 681-695 of human APP
-
APP
Fitzgerald
polyclonal
Goat
-
Human
-
APP
-
APP N-term
Fitzgerald
polyclonal
IgG
Goat
(neat serum, no preservative)
-
Human
immunogen = synthetic peptide corresp. to aa 44-63 on the N-terminus of APP
residues 44-63 on the N-terminus of APP
-
APP
Fitzgerald
polyclonal
Goat
-
-
-
APP
-
APP
Histo-Line
polyclonal
Goat
(liquid, neat serum, no preservatives)
-
Human
immunogen = synthetic peptide equivalent to aa681-695 of the C-terminal of human APP
APP C-terminal aa681-695
-
APP N-term
Histo-Line
polyclonal
IgG
Goat
(liquid, neat serum, no preservatives)
-
Human
immunogen = synthetic peptide equivalent to aa44-63 of the N-terminal of human APP
APP N-terminal aa44-63
-
APP frameshift mutant
Histo-Line
polyclonal
IgG
Goat
(liquid, neat serum, no preservatives)
-
Human
immunogen = synthetic peptide equivalent to aa339-348 of the C-terminal of human APP frameshift mutant
APP C-terminal aa339-348 of APPFM
-
β-APP (3G12)
Histo-Line
monoclonal
IgM
Mouse
(lyophilized, supernatant azide)
-
Human
immunogen = prokaryotic rh fusion protein corresp. to the extracellular protein of APP between the Kunitz protease inhibitor domain and the beta amyloid region
APP; no cross-reaction with APP-like proteins
-
APP (40.10)
Histo-Line
monoclonal
IgM
Mouse
(lyophilized, supernatant azide)
-
Human
immunogen = prokaryotic rh fusion protein corresp. to the extracellular protein of APP between the Kunitz protease inhibitor domain and the beta amyloid region
APP; no cross-reaction with APP-like proteins
-
sAPP
I B L-Hamburg GmbH
kit
IgG1
Unknown Host
(anti-mouse/rat APP; conj. anti-mouse/rat APP rabbit)
-
Mouse, Rat
-
sAPPα and full length APP
-
sAPPβ-sw (6A1)
I B L-Hamburg GmbH
monoclonal
IgG3
Mouse
(lyohilized, BSA, PBS, azide, supernatant protein-A purified)
-
Human
immunogen = synthetic peptide of the C-terminal part of human sAPPβ-sw (I S E V N L)
sAPPβ-sw type cleaved by β-secretase; no cross reaction with sAPPβ of wild type and the full length APP of both Swedish and wild types
-
sAPPβ-wild type
I B L-Hamburg GmbH
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, purified)
-
Human
immunogen = synthetic peptide in portion of C-terminus of human sAPPβ-Wild Type(I S E V K M)
detects sAPP-Wild type which is clevaged by β-secretase; no cross with sAPPα or full-length APP
-
sAPPα
I B L-Hamburg GmbH
polyclonal
IgG
Mouse
(lyophilized, BSA, PBS, azide, affinity purified)
-
Mouse, Rat
immunogen = synthetic peptide in portion of C-terminus of mouse/rat sAPPα (D A E F G H D S G F E V R H Q K)
detects sAPP-α; no cross-reaction with sAPPβ
-
sAPP
I B L-Hamburg GmbH
kit
Unknown Host
(mouse monoclonal anti-human APP; conj. anti-human sAPPα monoclonal mouse)
-
Human
-
detects soluble APP in samples as a total amount including sAPPα and sAPPβ
-
sAPPβ-wt
I B L-Hamburg GmbH
kit
Unknown Host
(rabbit polyclonal anti-human sAPPβ; conj. anti-human APP monoclonal mouse)
-
Human
-
detects soluble sAPPβ wild type
-
sAPPα
I B L-Hamburg GmbH
kit
Unknown Host
(mouse monoclonal anti-human sAPPα; conj. anti-human APP monoclonal mouse)
-
Human
-
detects soluble sAPPα
-
sAPPβ (Swedish type)
IBL
kit
Unknown Host
(96 well using 2 kinds of highly specific antibodies. Precoated plate with anti-Human sAPPβ-Swedish Type Rabbit IgG; labelled antibody HRP conjugated anti-Human APP (10D1) Mouse IgG Fab’)
-
Human
-
detects sAPPβ Swedish type in cell culture media
-
sAPPβ (wild type)
IBL
kit
Unknown Host
(96 well using 2 kinds of highly specific antibodies. Precoated plate with rabbit anti-Human sAPPβ-Wild Type; labeled antibody HRP conj. mouse anti-Human APP (10D1))
-
Human
-
detects sAPPβ wild type in cell culture media or cerebrospinal fluids.
-
APP βCTF
IBL
kit
IgG
Unknown Host
(Polyclonal rabbit anti-APP-C; monoclonal mouse anti-human Aβ(82E1))
-
Human
-
APP βCTF (β-secretase C-terminal fragment)
-
sAPP
IBL
kit
Unknown Host
(mouse monoclonal anti-human APP; conj. anti-human sAPPα monoclonal mouse)
-
Human
-
detects soluble APP in samples as a total amount including sAPPα and sAPPβ
-
sAPPα
IBL
kit
Unknown Host
(mouse monoclonal anti-human sAPPα; conj. anti-human APP monoclonal mouse)
-
Human
-
detects soluble sAPPα
-
APP (18)
IBL
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, affinity purified)
-
Human, Mouse, Rat
immunogen = synthetic peptide of a part of Human APP (L E V P T D G N A G L L A E P Q I A M F C)
detects APP; cross reacts with sAPPα and sAPPβ
-
APP (597)
IBL
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, affinity purified)
-
Mouse, Rat
immunogen = synthetic peptide in portion of C terminus of Mouse/Rat sAPPα(D A E F G H D S G F E V R H Q K)
detects APPα; no cross with sAPPβ
-
APP phosphorylated
IBL
polyclonal
IgG
Rabbit
(lyophilized, BSA, PBS, azide, affinity purified)
-
Human, Mouse
immunogen = synthetic peptide of phosphorylated part of APP(D A A V pT P E E)
detects phosphorylated APP; no cross with non phosphorylated APP
-