The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

29333 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
APP, APLP, AICD From manufacturers (14)
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, glycerol, thimerosal, affinity purified)
- Chicken, Human, Monkey, Mouse, Rat immunogen = synthetic peptide (E V D A A V T P E E R H L S K) corresp. to aa 737-751 of human AβPP or aa 85 to 99 of the C99 fragment generated by β- secretase cleavage. recognizes AβPP and its isoforms; not the two Aβ protein variants, Aβ 1-40 or Aβ 1-42. -
Abcam monoclonal
IgG1
Mouse
(liquid, PBS, glycerol, azide, protein G purified)
- Human, Rat immunogen = recombinant purified KPI domain of human APP (aa forms 770 and 771) expressed in P. pastoris recognizes the KPI domain of APP -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, azide)
- Human, Mouse, Rat immunogen = synthetic peptide corresponding to residues 653-662 of human amyloid A4 protein precursor; seq. is identical to those of rabbit, pig, bovine, guinea pig and chicken APP -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, azide)
- Human, Mouse, Rat immunogen = synthetic peptide corresp. to residues 737-751 of human amyloid A4 protein precursor APP -
A B R - Thermo Scientific polyclonal
IgY
Chicken
(liquid, PBS, azide)
- Human immunogen = purified recombinant APP corresp. to the chromosome 21 gene (human) APP, 120kDa -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, glycerol, azide)
- Human immunogen = synthetic peptides corresp. to residues R(653) P G S G L T N I K T E E(665) of human Amyloid beta A4 protein precursor (APP), isoform A APP -
A B R - Thermo Scientific polyclonal
Goat
(liquid, azide)
- Human immunogen = synthetic peptides corresp. to aa339-348 of the C-terminus of APP frameshift mutant APP frameshift mutant -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, azide)
- Human, Monkey, Mouse immunogen = proprietary APP -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, azide)
- Rat immunogen = synthetic peptide corresp. to the C-terminal region of rat APP APP -
A B R - Thermo Scientific polyclonal
Goat
(liquid, serum, azide)
- Human immunogen = synthetic peptide corresp. to aa681-695 at the C-terminus of APP APP -
A B R - Thermo Scientific polyclonal
Goat
(liquid, serum, azide)
- Human immunogen = synthetic peptide corresp. to aa339-348 of the C-terminus of APP frameshift mutant APP Frameshift Mutant -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, azide)
- Human, Mouse, Rat immunogen = synthetic peptide corresp. to aa653-662 of human APP or 1-10 of the Beta amyloid peptide APP, N-terminal -
A B R - Thermo Scientific polyclonal
Rabbit
(liquid, serum, azide)
- Primate (various), Human immunogen = synthetic peptide composed of aa292-312 from the KPI domain of human APP APP -
A B R - Thermo Scientific polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
- Human, Mouse, Rat immunogen = synthetic peptide corresp. to residues 737-751 of human APP; this seq. corresp. to aa85-99 of the C99 fragment APP, C-terminal; recognizes both intact APP and C99 fragment -
Amyloid-β From manufacturers (1)
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, supernatant, azide)
- Bovine, Human, Monkey immunogen = amyloid-β 1-16 conjugated to KLH amyloid-β 1-16 -
Apolipoproteins From manufacturers (62)
Novus Biologicals polyclonal
Mouse
(liquid, sera, no preservative)
- Human immunogen = partial recombinant APOBEC3F (NP_660341, aa274-373) APOBEC3F - apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -
Novus Biologicals polyclonal
Mouse
(liquid, sera, no preservative)
- Human immunogen = :partial recombinant APOBEC3G(NP_068594, aa 80-182) APOBEC3G - apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, purified, no preservative)
- Human immunogen = APOC1 (AAH09698, aa1-84) full length recombinant protein with GST tag APOC1 - apolipoprotein C-I -
Novus Biologicals polyclonal
Mouse
(liquid, sera, no preservative)
- Human immunogen = full length recombinant APOC1 (AAH09698, aa1-84) APOC1-apolipoprotein C-I -
Novus Biologicals polyclonal
IgG
Goat
(liquid, BBS, EDTA, azide)
- Human immunogen = full length synthetic apoLipoprotein type C-I (purified) apolipoprotein C-I; negligible cross-reactivity with Type A-I, A-II, B, C-II, C-III, E and J apoLipoproteins -
Novus Biologicals polyclonal
Mouse
(liquid, sera, no preservative)
- Human immunogen = partial recombinant APOC2 (AAH05348, aa23-102) APOC2 - apolipoprotein C-II -
Novus Biologicals polyclonal
IgG
Goat
(liquid, BBS, azide, affinity purified)
- Human immunogen = full length native apolipoprotein type C-II (purified) apolipoprotein C-II; negligible cross-reactivity with type A-I, A-II, B, C-I, C-III, E and J apoLipoproteins. -
Novus Biologicals polyclonal
IgG
Goat
(liquid, BBS, EDTA, azide, affinity purified)
- Human immunogen = full length native apolipoprotein type C-III (purified) apolipoprotein C-III; negligible cross-reactivity with type A-I, A-II, B, C-I, C-II, E and J apolipoproteins -
Novus Biologicals monoclonal
IgG2a
Mouse
(liquid, no preservative, purified)
- Human immunogen = full length recombinant APOC4 (AAH20723, aa27-128) APOC4 - apolipoprotein C-IV -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, PBS, azide, protein A purified)
- Human immunogen = recombinant full length human protein ApoJ -
Novus Biologicals polyclonal
IgG
Goat
(liquid, BBS, EDTA, azide, affinity purified)
- Human immunogen:purified recombinant full length protein (human) ApoJ (60 kDa); negligible cross-reactivity with Type A-I, A-II, B, C-I, C-II, C-III and E apoLipoproteins -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, no preservative, purified)
- Human immunogen = full length recombinant APOM (AAH20683, aa23-189) APOM - apolipoprotein M -
Novus Biologicals monoclonal
IgG2b
Mouse
(liquid, purified, no preserative)
- Human immunogen = full length recombinant APOM (AAH20683, aa23-189) APOM - apolipoprotein M -
Novus Biologicals polyclonal
Mouse
(liquid, sera, glycerol, no preservative)
- Human immunogen = full length recombinant APOM between aa23-189 NCBI#AAH20683 APOM - apolipoprotein M -
Novus Biologicals polyclonal
IgG
Goat
(liquid, sera, purified, TBS, BSA, azide, purified)
- Dog, Human immunogen = synethtic peptide, C-E K A L Q E Y R K K H R E E, representing the C-terminus of the human protein according to NP_001822.2; NP_976084.1 clusterin/APO-J; expected to recognise both reported isoforms (NP_001822.2 and NP_976084.1) -
Novus Biologicals polyclonal
Mouse
(liquid, sera, no preservative)
- Human immunogen = partial recombinant CLU (NP_001822, aa402-502) CLU - clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) -
Novus Biologicals monoclonal
IgG2a, κ
Mouse
(liquid, no preservative, purified)
- Human immunogen = partial recombinant APOL3 (NP_663615, aa240-337) APOL3-apolipoprotein L3 -
Polysciences, Inc. polyclonal
Goat
(liquid, affinity purified)
- Human, Mouse immunogen = ApoE derived from human plasma Apo E -
R&D Systems monoclonal
IgG
Goat
(lyophilized, PBS, trehalose)
- Human immunogen = rhApoE3 derived by E. coli ApoE3; less than 1% cross-reactivity with rhApoa1 and rhApoA2 -
R&D Systems monoclonal
IgG2a
Rat
(lyophilized, supernatant, PBS, trehalose, protein G purified)
- Human immunogen = rhApoE derived by E. coli, aa19-317 ApoE; no cross-reactivity with rhApoA1 or rhApoA2 -
RDI /Fitzgerald monoclonal
IgG1
Mouse
(lyophilized, no preservative, Ig fraction, protein G purified)
- Human immunogen = low density Apo E Apo E; no reaction to the other human serum proteins -
RDI /Fitzgerald monoclonal
IgG1
Mouse
(lyophilized, PBS, BSA, azide)
- Human immunogen = human Apo E detects all three common Apo E isoforms E2, E3, E4 -
RDI /Fitzgerald polyclonal
Rabbit
(lyophilized, PBS, sterile filtered)
- Human immunogen = highly pure (>98%) recombinant human Apo E3 Apo-E isoforms E2 and E4 -
RDI /Fitzgerald polyclonal
Goat
(liquid, Tris-saline, azide, affinity purified)
- Human immunogen = highly purified human Apo E Apo E -
RDI /Fitzgerald polyclonal
Goat
(liquid, delipidated serum, Tris-saline, azide)
- Human immunogen = human Apo E Apo E -
RDI /Fitzgerald polyclonal
Goat
(liquid, serum, azide, affinity purified)
- Human immunogen = purified human rhApo E Apo E; no cross reaction with A-I, A-II, A-IV, C-I, C-II, C-III, B and albumin -
RDI /Fitzgerald polyclonal
Rabbit
(liquid, serum, azide)
- - immunogen = synthetic peptide for the LDL receptor binding region (aa140-159), which includes one of the heparin-binding sites of the Apo E Apo E; no cross reaction with A-I, A-II, A-IV, C-I, C-II, C-III, B and albumin -
Santa Cruz polyclonal
IgG
Goat
(liquid, PBS, gelatin, azide, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping near the C-terminus of human ApoE ApoE (precursor and mature) -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, azide, gelatin)
- Human immunogen = purified ApoEof human origin detects all common ApoE isoforms -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, azide, gelatin)
- Human immunogen = a syntheticpeptide apoE spanning the polymorphic amino acid position 158 of human origin detects ApoE, 36 kDa -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = sequenced corresp. to aa. 31-353 mapping within an internal region of human apoE detects ApoE -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = sequenced corresp. to aa. 19-311 mapping at the C-terminus of apoE of mouse origin detects ApoE -
Autogen Bioclear monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human immunogen = synthetic peptide spanning the polymorphic aa position 158 of human ApoE ApoE -
AbD Serotec polyclonal
IgG
Goat
(liquid, Ig fract, PBS, azide, protein G purified)
- Rabbit, Human, Hamster immunogen = human Apolipoprotein E Apolipoprotein E; minimal cross reactivity with Apo A-1, A-2, B, C-2, C-3 and serum proteins. -
AbD Serotec polyclonal
IgG
Goat
(liquid, TBS, serum, azide, protein G purified)
- Human immunogen = highly purified ApoE ApoE -
AbD Serotec monoclonal
IgG1
Mouse
(lyophilized, mannitol, dextran and salts, affinity purified)
- Human immunogen = native Apo-A1 from human plasma reacts with both free human Apo-A1 and high density lipoprotein (HDL) bearing Apo-A1, but does not cross-react with ApoE, ApoB or Albumin -
AbD Serotec polyclonal
IgG
Rabbit
(lyophilized, ammonium sulfate ppt.)
- Human immunogen = purified Apolipoprotein A-1 Apolipoprotein A-1 -
AbD Serotec polyclonal
IgG
Rabbit
(liquid, PBS, azide, purified)
- Human immunogen = recombinant human clusterin isoform 1 Apolipoprotein J/clusterin (60kDa) -
AbD Serotec monoclonal
IgG1
Mouse
(liquid, BBS, azide, protein A purified)
- Human immunogen = Glomerular basement membrane from a post-mortem kidney Apolipoprotein J -
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, purified)
- Human - E4 isoforms of Apo-E Available from BioLegend
BioLegend monoclonal
IgG1
Mouse
(liquid, PBS, no preservative, protein A purified)
- Human - E4 isoforms of Apo-E Available from BioLegend
US Biological polyclonal
IgG
Goat
(serum, TBS, azide, delipidated serum)
- Human immunogen = human Apo E Apo E -
US Biological polyclonal
Goat
(liquid serum, sterile filtered, TBS, azide)
- Human immunogen = recomb. human Apo E Apo E isoforms E2, E3 and E4 -
US Biological polyclonal
IgG
Goat
(serum, BBS, azide, affinity purified)
- Human immunogen = full length native apolipoprotein type E (purified) Apo E; negligible crossreactivity with Type A-I, A-II, B, C-I, C-II, C-III and J apoLipoproteins -
US Biological polyclonal
IgG
Goat
(serum, TBS, BSA, azide, affinity purified)
- Chimpanzee, Human immunogen = synthetic peptide with sequence C-V G T S A A P V P S D N H, representing the C- terminus of the human protein according to NP_000032.1 Apo E -
US Biological polyclonal
Goat
(serum, TBS, BSA, azide, affinity purified)
- Human immunogen = synthetic peptide of ApoE Apo E (~36kDa) -
US Biological polyclonal
IgG
Goat
(serum, TBS, BSA, azide, affinity purified)
- Chimpanzee, Human immunogen = Synthetic peptide, C-V G T S A A P V P S D N H from the C-terminus of human APOE Apo E (~36kDa) -
US Biological polyclonal
IgG
Goat
(liquid, azide)
- Rabbit, Human immunogen = rabbit APOE Apo E -
US Biological polyclonal
IgG
Goat
(liquid, TBS, EDTA, azide, ammonium sulfate ppt.)
- Rabbit, Human immunogen = rabbit APOE Apo E -
US Biological polyclonal
IgG
Goat
(liquid, PBS, azide, protein G purified)
- Rabbit, Human, Hamster immunogen = human Apo E Apo E -
US Biological polyclonal
IgG
Goat
(liquid, serum, TBS, azide)
- Human immunogen = purified human Apo E Apo E -
US Biological polyclonal
IgG
Rabbit
(serum, PBS, azide)
- Human immunogen = synthetic peptide of human APOE receptor 2, conj. KLH Apo E Receptor 2 (LRP8) -
US Biological polyclonal
IgG
Rabbit
(serum, Tris-glycine saline, affinity purified)
- Human, Mouse immunogen = synthetic peptide made to a C-terminal portion of the human APOER2 protein sequence (between residues 863-963) Apo E Receptor 2 (LRP8) -
US Biological polyclonal
IgG
Rabbit
(serum, Tris-glycine saline, affinity purified)
- Chicken, Human, Mouse immunogen = synthetic peptide made to a C-terminal portion of the human APOER2 protein sequence (between residues 863-963) Apo E Receptor 2 (LRP8) -
US Biological polyclonal
IgG
Rabbit
(serum, Tris-glycine saline, affinity purified)
- Chicken, Human, Mouse immunogen = synthetic peptide made to a C-terminal portion of the human APOER2 protein sequence (between residues 800-900) Apo E Receptor 2 (LRP8) -
US Biological polyclonal
IgG
Goat
(serum, TBS, BSA, azide, affinity purified)
- Dog, Human, Mouse, Rat immunogen = synthetic peptide of APOER2 Apo E Receptor 2 (LRP8) (~90kD) -
US Biological polyclonal
IgG
Rabbit
(liquid, PBS, azide, affinity purified)
- Human immunogen = E. coli expressed recombinant human APOE2 ApoE2 -
US Biological polyclonal
IgG
Rabbit
(liquid, PBS, BSA, thimerosal, glycerol, affinity purified)
- Human immunogen = recombinant human APOE3 ApoE3 -
US Biological monoclonal
IgG1, κ
Mouse
(liquid, PBS, protein G purified, azide)
- Human immunogen = synthetic peptide corresp. to a region between aa140-160 of purified human ApoE Apo E -
US Biological polyclonal
Rabbit
(liquid, supernatant, tris-glycine saline, BSA, azide)
- Human immunogen = synthetic peptide corresp. to residues near the N-term of human apolipoprotein Apo E -
US Biological monoclonal
Mouse
(liquid, supernatant, tris-glycine saline, BSA, azide)
- Human immunogen = synthetic peptide corresp. to residues near the C-term of human apolipoprotein Apo E -
US Biological monoclonal
IgG
Rabbit
(liquid, supernatant, tris-glycine saline, BSA, azide)
- Human immunogen = synthetic peptide corresp. to residues near the N-term of human apolipoprotein Apo E, N-term -
ER Chaperones From manufacturers (1)
Stressgen Enzo Life Sciences polyclonal
Rabbit
(protein-A purified, PBS, azide, glycerol)
- Bovine, Rabbit, Quail, Sheep, Pig, Human, Monkey, Guinea Pig, Hamster, Mouse, Rat immunogen = synthetic peptide corresp. to amino acids 575-593 of canine calnexin conj. to KLH(sequence isidentical to mouse, human and rat) ~90 kDa Calnexin -
Growth Factors From manufacturers (12)
Calbiochem EMD Biosciences monoclonal
IgG1
Mouse
(affinity purified, PBS, trehalose, no preservative, lyophilized)
- Human immunogen = recomb. protein consisting of amino acids 129-247 of human BDNF recognizes the ~20 kDa BDNF protein -
Chemicon and Upstate are Millipore polyclonal
IgG1
Sheep
(protein-G purified, PBS, no preservative, lyophilized)
- Chicken, Human, Rat immunogen = recomb. human BDNF BDNF; by one site ELISA, less than 1% cross-reactivity against mouse NGF, recomb. human NT3 or neurotrophin 4 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(whole antiserum, no preservative, lyophilized)
- Human, Mouse, Rat immunogen = 10 aa. peptide corresp. to the amino-terminal of mouse BDNF, coupled to ovalbumin BDNF; does not cross-react with NT3 or NGF -
Chemicon and Upstate are Millipore polyclonal
IgG1
Sheep
(serum, no preservative, lyophilized)
- Chicken, Human, Rat immunogen = recomb. human BDNF BDNF; by one site ELISA, less than 1% cross-reactivity against mouse NGF, recomb. human NT3 or neurotrophin 4 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(protein-A purified Ig, no preservative, lyophilized)
- Human, Mouse, Rat immunogen = 10 aa. peptide corresp. to the amino-terminal of mouse BDNF, coupled to ovalbumin BDNF; less than 1% cross with mouse NGF, recomb. human NT3 or neurotrophin 4 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(serum, no preservative, lyophilized)
- Human, Rat immunogen = recomb. human BDNF BDNF; By DB, less than 1% cross against NGF, NT3 or NT4 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(Ig fraction, PBS, no preservative, lyophilized)
- Human, Rat immunogen = recomb. human BDNF BDNF; By DB, less than 1% cross against NGF, NT3 or NT4 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(affinity purified Ig, PBS, no preservative, lyophilized)
- Human, Rat immunogen = 10 aa. peptide corresp. to the amino-terminal of mouse BDNF BDNF; by DB, -
Chemicon and Upstate are Millipore polyclonal
Chicken
(liquid, affinity purified Ig, PBS, azide)
- Human, Mouse immunogen = synthetic peptides from human BDNF reacts with BDNF -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(serum, lyophilized)
- Rat immunogen = recomb. human BDNF BDNF; By WB, reacts with recomb. BDNF protein and also detects the ~28 kDa proBDNF; shows no cross with NGF, NT3 or NT4/5 -
Chemicon and Upstate are Millipore polyclonal
Rabbit
(affinity purified, PBS, no preservative, lyophilized)
- Human, Mouse, Rat immunogen = synthetic peptide from human proBDNF 35 kDa pro BDNF; does not cross-react with other pro neurotrophins -
Chemicon and Upstate are Millipore polyclonal
Chicken
(liquid, semi-purified Ig)
- Human, Mouse, Rat immunogen = fusion protein from mouse proBDNF containing only the prodomain region reacts with proBDNF. Does not recognize mature BDNF isoforms -
Neuronal Markers From manufacturers (1)
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, purified Ig, AlexaFluor® 488 conj, PBS, BSA, azide)
- Human, Mouse, Rat immunogen = purified cell nuclei from mouse brain reacts with most neuronal cell types; is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells -
Organelles From manufacturers (7)
DSHB U. Iowa monoclonal
IgG1
Mouse
(liquid, available as supernatant, concentrate, ascites)
- Human immunogen = human Lamp-2 Lamp-2 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
- Human immunogen = synthetic peptide corresp. to residues G(a.a. 368)QVMESVRQ LQMERDK(a.a. 383) of human GM130 detects GM130; an approx. 135 kDa band -
Novus Biologicals polyclonal
IgG
Mouse
(liquid, antisera, no preservativeAlso available purified, H00002801-B01P)
- Human immunogen = GOLGA2 (1 a.a. ~ 345 a.a) full-length human protein detects GOLGA2/GM130; reactive against immunizing recombinant protein, transfected lysate and tissue lysate for WB -
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, purified IgG, PBS, no preservative)
- Human immunogen = GOLGB1 (NP_004478, 3 a.a. ~ 92 a.a) partial recomb. protein with GST tag detects giantin; reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control -
Alexis Enzo Life Sciences monoclonal
IgG1
Mouse
(affinity purified, gel filtrated (FPLC), lyophilized)
- Mammal (various), Avian (various), Human, Monkey immunogen = Giantin from Caco-2 cell Golgi membrane fraction Recognizes giantin -
Zymed/ Invitrogen polyclonal
Ig
Rabbit
(serum, affinity purified, PBS, azide)
- Rat immunogen = synthetic peptide derived from the cytosolic region of the rat Lamp-2 (lgp96) protein detects the ~96 kDa rat Lamp-2 (lgp96) -
BD Pharmingen monoclonal
IgG2a, κ
Rat
(liquid, affinity purified, aqueous, buffered, azide, FITC conj.)
- Mouse immunogen = glycoproteins purified from BALB/c mouse embryo 3T3 cell line detects LAMP-2 -
SOD From manufacturers (1)
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, gelatin, azide)
- Human, Mouse, Rat (epitope mapping between amino acids 120-146 at the C-terminus of SOD-1 of human origin) detects SOD-1 -
Tubulin From manufacturers (1)
Sigma Aldrich monoclonal
IgG1
Mouse
(liquid, purified IgG, PBS, azide)
- Bovine, Chicken, Sea Urchin, Chlamydomonas, Human, Monkey, Mouse, Rat immunogen = Sarkosyl-resistant filaments from sea urchin recognizes an epitope located at the C-terminal end of alpha-tubulin -