The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

29333 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
BrdU From manufacturers (11)
Axxora monoclonal
IgG1
Mouse
(liquid, PBS, azide; available biotinylated or FITC conj.)
- - immunogen = IU(iodouridine) conjugated ovalbumin BrdU and IU either free, within single-stranded DNA or coupled to a protein carrier; no cross with thymidine -
Axxora monoclonal
IgG1
Mouse
(buffered, unconjugated)
- - immunogen = iodouridine conjugated ovalbumin BrdU in ssDNA, free BrdU, or BrdU coupled to a protein carrier. Cross with iodouridine but not thymidine -
Axxora monoclonal
IgG1
Mouse
(buffered, FITC conj)
- - immunogen = iodouridine conjugated ovalbumin BrdU in ssDNA, free BrdU, or BrdU coupled to a protein carrier. Cross with iodouridine but not thymidine -
Axxora monoclonal
IgG1
Mouse
(buffered, Biotin conj)
- - immunogen = iodouridine conjugated ovalbumin BrdU in ssDNA, free BrdU, or BrdU coupled to a protein carrier. Cross with iodouridine but not thymidine -
Axxora monoclonal
IgG1
Mouse
(buffered, Alexa Fluor® 488 conj.)
- - immunogen = iodouridine conjugated ovalbumin BrdU in ssDNA, free BrdU, or BrdU coupled to a protein carrier. Cross with iodouridine but not thymidine -
Axxora monoclonal
IgG1
Mouse
(buffered, Alexa Fluor® 647 conj.)
- - immunogen = iodouridine conjugated ovalbumin BrdU in ssDNA, free BrdU, or BrdU coupled to a protein carrier. Cross with iodouridine but not thymidine -
Axxora monoclonal
IgG1
Mouse
(buffered, Phoenix Red conj.)
- - immunogen = iodouridine conjugated ovalbumin BrdU in ssDNA, free BrdU, or BrdU coupled to a protein carrier. Cross with iodouridine but not thymidine -
Axxora kit
Mouse
(high sensitivity by Dual Color Flow Cytometry; use of a fluorescein labelled anti-BrdU monoclonal antibody, ALX-804-197, gives rise to a stronger signal in flow cytometry)
- Various species   for measuring apoptosis with high sensitivity by Dual Color Flow Cytometry in mammalian cells. measures BrdU, and Br-dUTP in the genome -
Biocare Medical monoclonal
IgG1
Mouse
(Biotinylated, liquid, buffer with protein carrier and preservative)
- Various species immunogen = BrdU recognizes BrdU -
Biodesign Meridian LifeScience monoclonal
IgG1κ
Mouse
(ascites, PBS, azide, protein A purified, azide)
- Various species   BrdU -
Biodesign Meridian LifeScience monoclonal
IgG2a
Mouse
(supernat, Protein A, liquid, azide, FITC)
- Various species BrdU BrdU -
FGF & FGF Receptors From manufacturers (81)
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, azide, gelatin)
- Human Immunogen = amino acids 25-124 of hFGFR-3 detects FGFR-3 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping at the C-terminus of hFGFR-3 detects FGFR-3 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human, Mouse, Rat Immunogen = amino acids 25-124 of hFGFR-3 detects FGFR-3 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, affinity purified, PBS, azide, gelatin)
- Human immunogen = peptide mapping at the C-terminus of hFGFR-4 detects FGFR-4 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Mouse, Rat immunogen = peptide mapping at the C-terminus of mouse FGFR-4 detects FGFR-4 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human, Mouse, Rat Immunogen = amino acids 25-145 mapping within an extracellular domain of hFGFR-4 detects FGFR-4 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping within an internal region of hFGFR-5 detects FGFR-5 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping near the C-terminus of hFGFR-5 detects FGFR-5 -
Santa Cruz monoclonal
IgG2a
Mouse
(liquid, PBS, azide, protein stabilizer)
- Human immunogen = extracellulardomain of human FGFR-4 detects FGFR-4, 88 kDa -
Santa Cruz monoclonal
IgG1
Mouse
(liquid, PBS, azide, gelatin)
- Human immunogen = amino acids 25-145 of human FGFR-4 detects FGFR-4, 88 kDa -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = shortamino acid sequence containing phosphorylated Tyr 724 of human FGFR-3 detects FGF-3 phosphorylated at Tyr 724 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping within a cytoplasmic domain of hFGFR-3 detects FGFR-3 -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping within a cytoplasmic domain of hFGFR-3 detects FGF-3 -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatinAlso available as goat, sc-122-G)
- Dog, Human, Mouse, Rat immunogen = peptide mapping within a C-terminalcytoplasmic domain of human Bek Bek; No cross reactivity with Flg, FGFR-3 or FGFR-4. -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat Peptide mapping within an N-terminal extracellular domain of human Bek detects Bek (FGFR-2) -
Santa Cruz polyclonal
IgG
Goat
(liquid, affinity purified, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = peptide mapping within an extracellular domain of hBek detects Bek; 120 kDa -
Santa Cruz polyclonal
IgG
Rabbit
(liquid, PBS, azide, gelatin)
- Human, Mouse, Rat Immunogen = amino acids 22-101, near the N-terminus of human Bek detects Bek; 120 kDa -
Santa Cruz monoclonal
IgG2b
Mouse
(liquid IgG, PBS, azide, protein stabilizerAlso azide-free, SC-73738 L)
- Human immunogen = full lengthrecombinant Bek of human origin detects Bek (FGFR-2); 120 kDa -
Santa Cruz monoclonal
IgG2b
Mouse
(liquid IgG, PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = epitope mappingbetween amino acids 795-821 at the C-terminus of human Bek receptor FGFR-2; identical to corr. mouse sequence detects Bek (FGFR-2); 120 kDa -
AbD Serotec monoclonal
IgG2a
Mouse
(liquid, supernate, PBS, azide, protein G purified)
- Human Immunogen = recombinant human bFGF FGF-basic; binds strongly to bFGF attached to proteoglycans, but is competitively displaced by heparin; not suitable for detecting bFGF bound to cell surface receptors -
AbD Serotec polyclonal
Rabbit
(lyophilized, PBS, no preservative, affinity purified)
- Human Immunogen = recombinant human FGF-basic FGF-basic, aka FGF-2 (fibroblast growth factor 2), a member of the heparin-binding growth factor family which exists in both cytosolic and nuclear isoforms, ranging in size from 18-24kDa, expressed by the majority of cells and tissues -
AbD Serotec polyclonal
Rabbit
(lyophilized, PBS, no preservative, affinity purified; biotinylated)
- Human Immunogen = recombinant mouse FGF-basic FGF-basic, aka FGF-2 (fibroblast growth factor 2), a member of the heparin-binding growth factor family which exists in both cytosolic and nuclear isoforms, ranging in size from 18-24kDa, expressed by the majority of cells and tissues -
AbD Serotec polyclonal
Rabbit
(liquid, IgG fraction, PBS, azide)
- Bovine, Human, Mouse, Rat Immunogen = R-DNA detects FGF-basic -
AbD Serotec polyclonal
IgG
Rabbit
(lyophilized, affinity purified, PBS, no preservatives or stabilizers)
- Mouse Immunogen = recombinant mouse FGF-9 (highly purified) detects FGF-9 -
AbD Serotec polyclonal
IgG
Rabbit
(lyophilized, affinity purified, biotinylated)
- Mouse Immunogen = highly purified recombinant mouse FGF-9 FGF-9 -
AbD Serotec monoclonal
IgM
Mouse
(liquid, PBS, NaCl, azide)
- Bovine, Chicken, Human, Mouse, Rat Immunogen = FGF receptor purified from bovine coronary venular endothelial cells FGF-receptor, flg gene product; it is believed to react with a protein epitope rather than carbohydrate receptor epitope; also reacts with the bek gene product but to a lesser degree -
Sigma Aldrich monoclonal
IgG2a
Mouse
(liquid, purified, sterile filtered, PBS)
- Bovine, Human immunogen = recombinant human FGF acidic; epitope at or near receptor binding site of aFGF native and recombinant human FGF acidicic,human FGF-basic -
Sigma Aldrich polyclonal
IgG
Rabbit
(protein-A, PBS, affinity purified, no preservative, lyophilized)
- Bovine, Human immunogen = purified native bovine FGF acidic FGF acidic, not FGF basic -
Sigma Aldrich monoclonal
IgG1
Mouse
(liquid, sterile filtered, PBS)
- Bovine, Human immunogen = recombinant human FGF basic native and recombinant human FGF basic,not human FGF-acidic -
Sigma Aldrich polyclonal
IgG
Rabbit
(sterile filtered, KLH, PBS, no preservative, lyophilized)
- Bovine, Human immunogen = synthetic peptides corr. to aa 1-24 of bovine FGF basic FGF basic, not FGF acidic or BSA -
Sigma Aldrich polyclonal
IgG
Rabbit
(liquid IgG fraction, sterile filtered, PBS, azide)
- Human immunogen = purified recomb. human FGF basic, expressed in E. coli detects FGF basic, not recomb. human FGF-acidic, IL-1α,IL-1β, IL-3 or TNF-α, nor with mouse or human IL-6 -
Sigma Aldrich polyclonal
IgG
Goat
(lyophilized, affinity purified)
- Human Immunogen = recombinant hFGF-10 expressed in E. coli rhFGF-10~30% cross-reactivity with rhFGF-7 and 15% with rhFGF-5 -
Sigma Aldrich polyclonal
IgG
Goat
(lyophilized, affinity purified)
- Human Immunogen = recombinant hFGF-18 (purified, E.coli derived) rhFGF-186% cross-reactivity with hFGF-17, m and hFGF-8b, mFGF-8c. No cross with hFGF acidic, hFGF basic, hFGF-4, hFGF-6, hFGF-7, hFGF-9, and hFGF-10 -
Sigma Aldrich monoclonal
IgG1
Mouse
(lyophilized, protein A purified, PBS, no preservative)
- Human Immunogen = recombinant hFGF-4 (purified, E. coli derived) detects recombinant FGF-4; does not cross with bovine FGF-acidic, rhFGF-acidic, bovine FGF-basic, rhFGF-basic, and rhβ-ECGF -
Sigma Aldrich monoclonal
IgG1
Mouse
(lyophilized, Protein G purified, PBS, trehalose)
- Human, Mouse Immunogen = recombinant hFGF-8b, purified, E. coli derived FGF-8b, FGF-8c -
Sigma Aldrich monoclonal
IgG1
Mouse
(liquid, purified, PBS, sterilized)
- Human, Mouse immunogen = recombinant mouse FGF-9 detects recombinant FGF9, no cross with human aFGF or bFGF -
Sigma Aldrich polyclonal
IgG
Rabbit
(liquid IgG fraction, purified, PBS, azide)
- Human immunogen = synthetic peptides corr. to aa 55-68 and 150-162 of FGF-9, conj to KLH recomb. FGF9, no cross with rhFGF acidic or rhFGF basic -
Sigma Aldrich polyclonal
Ig
Rabbit
(liquid, affinity isolated, PBS, BSA, azide)
- Human immunogen = synthetic peptide corr. to aa 360-373 of extra cellular region of human FGFR-1 detects FGFR-1; no cross wirh FGFR-2 or FGFR-3 -
Sigma Aldrich polyclonal
Ig
Rabbit
(liquid, affinity isolated, PBS, BSA, azide)
- Human immunogen = synthetic peptide corr. to aa 809-821 of C-terminal region of human FGFR-2, with N-terminal added lysine, conj to KLH detects cytoplasmic FGFR-2, no cross with FGFR-1 or FGFR-3 -
Sigma Aldrich polyclonal
Ig
Rabbit
(liquid, affinity isolated, PBS, BSA, azide)
- Human immunogen = synthetic peptide corr. to aa 362-374 of extracellular region of human FGFR-2 (Bek), conj to KLH FGFR-2, in extracts of transfected cells, not human FGFR-1 or FGFR-3 -
Sigma Aldrich polyclonal
Ig
Rabbit
(liquid, affinity purified, PBS, BSA, azide)
- Human Immunogen = synthetic peptide corresp. to amino acids 792-806 of the cytoplasmic region of hFGFR-3 with N-terminal added lysine detects FGFR-3; no cross with FGFR-1 and FGFR-2 -
Sigma Aldrich polyclonal
Ig
Rabbit
(liquid, affinity purified, PBS, azide, BSA)
- Human Immunogen = synthetic peptide corresp. to amino acids 359-372 of extracellular region of hFGFR-3 detects FGFR-3 extracellular -
BD Transduction monoclonal
IgG1
Mouse
(liquid, buffered, BSA, glycerol, HRPO)
- Dog, Chicken, Human, Mouse, Rat Immunogen = full length human FGF basic FGF basic, 18-24 kda by WB -
BD Transduction monoclonal
IgG1
Mouse
(liquid, buffered, BSA, azide, glycerol)
- Dog, Chicken, Human, Mouse, Rat Immunogen = full length human FGF basic FGF basic, 18-24 kda by WB -
BD Transduction monoclonal
IgG1
Mouse
(liquid, buffered, BSA, glycerol, azide)
- Dog, Chicken, Human, Mouse, Rat Immunogen = full length human FGF basic FGF basic, 18-24 kda by WB -
BD Transduction monoclonal
IgG1
Mouse
(liquid, buffered, BSA, glycerol, azide)
- Dog, Chicken, Human, Mouse, Rat Immunogen = full length human FGF basic FGF basic, 18-24 kda by WB -
US Biological monoclonal
IgM
Mouse
(affinity purified, liquid, Tris)
- Human immunogen = purified human recombinant acidic FGF expressed in yeast cells FGF acidic -
US Biological polyclonal
IgG
Rabbit
(affinity purified antiserum, lyophilized)
- Human immunogen = highly purified human recombinant antigen FGF acidic -
US Biological polyclonal
IgG
Rabbit
(affinity purified antiserum, PBS, Biotin, lyophilized)
- Human immunogen = highly purified recombinant antigen detects FGF acidic -
US Biological polyclonal
Rabbit
(affinity purified, liquid, Tris-HCl)
- Human immunogen = human recombinant acidic FGF FGF acidic -
US Biological monoclonal
IgG1κ
Mouse
(liquid, DEAE-52 purified, PBS, glycerol)
- Bovine, Human, Mouse, Rat immunogen = purified bovine brain basic FGF recognizes native and heat-inactivated bovine FGF basic; not bovine FGF acidic -
US Biological monoclonal
IgG1κ
Mouse
(liquid, DEAE purified, glycerol, TBS, no preservative)
- Bovine, Human, Mouse, Rat immunogen = purified bovine brain basic FGF recognizes non-denatured form of bovine basic fgf; no cross with bovine acidic fgf -
US Biological monoclonal
IgG1κ
Mouse
(liquid, DEAE purified, TBS, glycerol, no preservative)
- Bovine, Human, Mouse, Rat immunogen = purified bovine brain basic FGF recognizes non-denatured form of bovine basic fgf; no cross with bovine acidic fgf -
US Biological monoclonal
IgG1
Mouse
(affinity purified, liquid, PBS, glycerol)
- Human immunogen = purified human recombinant basic FGF expressed in yeast cells recognizes rhFGF basic; not rhFGF acidic -
US Biological monoclonal
IgG1
Mouse
(protein-G affinity purified, PBS, lyophilized)
- Human immunogen = recombinant human basic FGF detects FGF-basic -
US Biological polyclonal
IgG
Rabbit
(affinity purified, PBS, lyophilized)
- Human immunogen = highly purified recombinant basic FGF recognizes FGF-basic -
US Biological monoclonal
IgG1
Mouse
(lyophilized, Protein G purified, PBS)
- Human Immunogen = purified recombinant human FGF-basic detects FGF-basic -
US Biological monoclonal
IgG1
Mouse
(lyophilized, Protien G purified, PBS)
- Human Immunogen = purified recombinant human FGF-basic detects FGF-basic -
US Biological monoclonal
IgG1
Mouse
(lyophilized, Protein G purified, PBS)
- Human Immunogen = purified recombinant human FGF-basic detects FGF-basic -
US Biological monoclonal
IgG1
Mouse
(lyophilized, Protein G purified, PBS)
- Human Immunogen = purified recombinant human FGF-basic detects FGF-basic -
US Biological monoclonal
IgG2a
Mouse
(lyophilized, protein G purified, PBS)
- Human Immunogen = purified recombinant human FGF-basic detects FGF-basic -
US Biological monoclonal
IgG2a
Mouse
(lyophilized, Protein G purified, PBS)
- Human Immunogen = purified recombinant human FGF-basic detects FGF-basic -
US Biological monoclonal
IgG2a
Mouse
(liquid, protein G purified, PBS, azide)
- Human Immunogen = recombinant human FGF-basic recognizes FGF-basicBinds strongly to bFGF attached to proteoglycans, but is completely displaced by heparin.Not suitable for detecting bFGF bound to cell surface receptors. -
US Biological monoclonal
IgG
Rabbit
(liquid, buffer, glycerol)
- Human, Rat Immunogen = synthetic peptide (GFFLRIHPDGRVDGVREKSDPHIK), corresp. to amino acids 40-63 of Human fgf basic detects FGF-basic -
US Biological monoclonal
IgG2a
Mouse
(liquid, affinity purified, PBS, azide)
- Human immunogen = recombinant full length human protein detects FGF basic; binds strongly to bfgf attached to proteoglycans, but is competitively displaced by heparin -
US Biological polyclonal
IgG
Rabbit
(affinity purified serum, PBS, Biotin, lyophilized)
- Human immunogen = highly purified recombinant human FGF basic detects FGF basic -
US Biological polyclonal
IgG
Rabbit
(lyophilized PBS, affinity purified)
- Human immunogen = highly pure recombinant human FGF-basic recognizes FGF-basic -
US Biological polyclonal
IgG
Rabbit
(lyophilized PBS, affinity purified, biotinylated)
- Human Immunogen = recombinant human FGF-basic (highly pure) recognizes FGF-basic -
US Biological monoclonal
IgG1
Mouse
(affinity purified lyophilized)
- Human immunogen = recombinant human fgf basic FGF-basic, 100%, no reactivity to acytokine panel -
US Biological polyclonal
IgG
Rabbit
(sterile-filtered, PBS, lyophilized)
- Human immunogen = recombinant human FGF basic recognizes FGF-basic -
US Biological polyclonal
IgG
Goat
(lyophilized PBS, affinity purified)
- Human, Mouse Immunogen = recombinant human FGF-10, >98% pure detects FGF-10 -
US Biological monoclonal
IgG1
Mouse
(liquid, PBS, Protein A purified, no preservative)
- Human Immunogen = recombinant human FGF-5 FGF-5 -
US Biological polyclonal
IgG
Goat
(lyophilized PBS, Protein A purified)
- Human Immunogen = recombinant human FGF-10, highly pure recognizes FGF-10 -
US Biological monoclonal
IgG1
Mouse
(liquid PBS, glycerol, Protein A purified)
- Human Immunogen = recombinant human FGF-6 derived from E. coli FGF-6 Will not neutralize activity of FGF-acidic, basic, rhFGF-4 or -5. Based on ELISA shows ~75% reactivity with rhFGF-5 and -
US Biological polyclonal
IgG
Goat
(liquid PBS, affinity purified)
- Human Immunogen = recombinant human FGF-6 derived from E. coli recognizes FGF-6 cross-reactivity: ~50% rhFGF-4; -
US Biological polyclonal
IgG
Goat
(lyophilized PBS, affinity purified, biotinylated)
- Human Immunogen = recombinant human FGF-6 derived from E. coli recognizes FGF-6 cross-reactivity: ~40%rhFGF-4; ≤ 10% rhFGF-9; ≤ 5% rhFGF-5 and FGF-basic -
US Biological polyclonal
IgG
Rabbit
(affinity purified, PBS, Biotin conj, lyophilized)
- - immunogen = highly purified recombinant mouse FGF-9 recognizes FGF-9 -
US Biological polyclonal
IgG
Rabbit
(affinity purified, PBS, lyophilized)
- Mouse immunogen = highly purified recombinant mouse FGF-9 recognizes 5B FGF-9 -
US Biological polyclonal
IgG
Rabbit
(lyophilized PBS, affinity purified)
- Mouse Immunogen = recombinant murine FGF-9 recognizes FGF-9 -
US Biological monoclonal
IgG1
Mouse
(protein-A affinity purified, PBS, serum)
- Human, Mouse Immunogen = full length recombinant murine FGF-9 reacts specifically with recombinant fgf9 (fibroblast growth factor 9). It does not crossreact with human FGF Acidic and FGF Basic -
US Biological polyclonal
IgG
Rabbit
(lyophilized PBS, affinity purified, biotin conj.)
- Mouse Immunogen = recombinant murine FGF-9 FGF-9 -
Synaptic Vesicle Fusion From manufacturers (4)
DSHB U. Iowa monoclonal
IgG2aκ
Mouse
(concentrate or supernatant or ascites)
- Zebra fish immunogen = neuropil region and primary motor neuron axons of zebrafish synaptotagmin, neuropil and primary motor neuron axons -
Stressgen Enzo Life Sciences monoclonal
IgG2A
Mouse
(liquid, protein-G purified, PBS, azide, glycerol)
- Mouse, Rat Immunogen = recombinant rat Bassoon protein detects bassoon -
Synaptic Systems monoclonal
IgG2b
Mouse
(hybridoma supernatant, lyophilized)
- Mouse, Rat immunogen = recombinant protein containing the 330 C-terminal aa of rat bassoon detects bassoon -
Synaptic Systems polyclonal
Rabbit
(antiserum, lyophilizedalso available affinity purified, lyophilized, Cat# 141 003)
- Mouse, Rat immunogen = 330 C-terminal aa. of rat bassoon detects bassoon protein, apparent MW: 420 kDa -
Tau From manufacturers (4)
RDI /Fitzgerald monoclonal
IgG1
Mouse
(purified ascites, PBS, BSA, azide)
- Cow, Sheep, Human, Mouse, Rat immunogen = purified bovine microtubule associated proteins detects tau in neurofibrillary tangles, neuropil threads, neuritic plaques, astrocytes and ribosomes. -
RDI /Fitzgerald monoclonal
IgG1
Mouse
(liquid, purified, PBS, BSA, azide)
- Cow, Sheep, Human, Mouse, Rat immunogen = purified bovine microtubule associated proteins reacts with 45-68 kDa tau proteins. There is no cross reaction withMAPs or tubulin. -
Epitomics monoclonal
IgG
Rabbit
(frozen liquid, tris-glycine, NaCl, glycerol, azide, BSA)
- Human, Rat Immunogen = synthetic phospho-peptide corresponding to residues surrounding Ser396 of human tau Tau phosphorylated on Ser 396 -
DSHB U. Iowa monoclonal
IgG1
Mouse
(purified)
- Human immunogen = human recomb. tau (epitope between aa 19-46) 6 different isoforms from ~ 45-58 kDa in human brain -