The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

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	Name	Source	Clonality & Isotype	Host & Formulation	Method	Reactivity	Immunogen/ Epitope	Specificity	Availability
Amyloid-β From labs (1)
	Aβ (3D6)	Elan Pharmaceuticals	monoclonal	Mouse	-	Human, Mouse	immunogen = synthetic peptide fragment conjugated to sheep anti-mouse immunoglobulin; epitope at aa 1-5 within Aβ42	Aβ (recognizes amino acids 1-5). Does not recognize secreted APP or APP-FL. Detects only Aβ species with amino-terminal aspartic acid.	-
Amyloid-β From manufacturers (1)
	Amyloid β [1-42] and Aβ [1-40]	Innogenetics	kit	Unknown Host (well standardized multiparameter bead-based immunoassay for the simultaneous quantification of human ß-amyloid in plasma using xMAP® (registered trademark of Luminex Corp)technology)	-	Human	Uses 3D6 antibody;3D6 selectively binds Aß peptides with a free aminogroup at Asp1 (epitope 1–5)	for simultaneous quantification of different forms of β-amyloid in blood, with check for matrix interference	-
Mitochondrial Proteins, Microglial Markers From manufacturers (1)
	Anti-PBR antibody (EPR5384)	Abcam Cat# ab109497	monoclonal IgG	Rabbit (Tissue culture supernatant. PBS 49 percent, sodium azide 0.01 percent, glycerol 50 percent, BSA 0.05 percent.)	-	Human, Mouse	A synthetic peptide corresponding to residues at the C-terminus of human peripheral benzodiazepine receptor (PBR)/translocator protein (TSPO).	This antibody recognizes PBR, also known as TSPO, a mitochondrial transporter that is upregulated in activated microglia.	Confirmed available December 2014.
TAR DNA-binding protein /TDP-43 From manufacturers (1)
	Anti-phospho TDP-43 (ser409/410) (1D3)	Millipore Cat# MABN14	monoclonal IgG2ak	Rat (Purified in buffer containing 0.1 M Tris glycine with 0.05% sodium azide)	-	Human	Ovalbumin-conjugated linear peptide corresponding to human TDP-43 phosphorylated at serine 409 and 410.	This antibody recognizes human TDP-43 phosphorylated at serine 409 and 410.	Confirmed Oct 2014
Tau From manufacturers (2)
	Tau phos Thr181 (AT270)	Innogenetics	monoclonal IgG1κ	Mouse (liquid, sterile filtered, PBS, no preservative, affinity purified)	-	Human	immunogen = human tau40, aa. around phospho. Thr 181	specific for tau phospho at Thr 181; as PHF-tau, tangles and neurofilaments; weak cross with normal tau;	-
	Tau (AT8)	Pierce Thermo Scientific Cat#  MN-1020	monoclonal IgG1κ	Mouse (Protein A affinity purified, PBS, no preservative)	-	Baboon, Human, Rabbit, Hamster, Avian (various), Drosophila	immunogen = partially purified human paired helical filament tau.	Recognizes tau protein phosphorylated at both serine 202 (Ser202) and threonine 205 (Thr205). Does not cross-react with unphosphorylated forms of tau.	Confirmed available April 2015.