New Parkinson’s Gene: DJ Mutations Make Neurons Change Their Tune
In today's SciencExpress, researchers from Italy, France, and The Netherlands report that mutations in DJ-1, a protein of unknown function, can lead to Parkinson's disease...
ALL NEWS
6545 RESULTS
Sort By:
- Most Recent
- Most Commented
Orlando: Medium-Throughput Target Discovery Using Brain Slices
Researchers led by Don Lo of Duke University Medical Center and Cogent Neuroscience, Inc., in Durham, North Carolina, have developed a novel brain-slice platform for identifying therapeutic targets for neurodegenerative diseases...
Age Factors into Survival after AD Diagnosis
People diagnosed with Alzheimer's disease at age 65 will likely live more than twice as long as those diagnosed at age 90, according to a study in the current issue of the Archives of Neurology...
MRI Keeps an Eye on Those Transplanted Stem Cells In Vivo
Embryonic stem (ES) cells have the inherent potential to replace or repair almost every tissue in the body. One key to this prowess is the ability to migrate...
Orlando: Early Results Hint That Insulin-Sensitizing Drug Improves Cognition
Insulin resistance is emerging as a possible risk factor for Alzheimer’s, and data from a pilot trial presented at the 2002 Neuroscience meeting indicate that an insulin-sensitizing drug may represent a novel treatment approach...
Spinal Taps for Tau Tests
Assays of Aβ or tau protein in cerebrospinal fluid can identify Alzheimer's disease in patients with mild cognitive impairment, say the authors of a study in today’s Archives of Neurology...
Can Travel, Will Deposit: Aβ via the Perforant Pathway?
Two studies indicate that the amyloid deposits found in the hippocampus may come not so much from local cells but arrive via the axons of distant neurons projecting there...
Cholinergic Neurons from Stem Cells—Another Step Toward a Distant Goal
The replacement of dying neurons in Alzheimer’s disease with neural stem cells remains a pie in the sky, but at least researchers now appear to have gotten their hands on the filling...
Mini-strokes from Passive Immunization?
Aβ immunotherapists are back at the drawing board after inflammatory complications scuttled the first clinical trial...
Orlando: Preliminary Results of NGF Gene Therapy Trial Are Mixed
Preliminary results of the NGF gene therapy clinical trial in early-stage AD illustrate the potential promise—and pitfalls—of gene therapy for neurodegenerative diseases...
Hormone Replacement Therapy Still up on Balance Beam
Use of hormone replacement therapy (HRT) appears to protect some women from Alzheimer's disease, according to a prospective observational study of AD risk factors published in this week's JAMA...
Orlando: ARF Awards 2002
It may not be the Oscars or Nobel prize, but recipients of the second annual Alzheimer Research Forum Awards were warmly applauded at the Society for Neuroscience meeting....
Orlando: ADDLing Pieces to the Amyloid Puzzle; Oligomers Increase in AD Brain
In three posters on Wednesday here at the annual Neuroscience meeting, <strong>William Klein's</strong> laboratory extended their earlier presentation to add new pieces to the puzzle of the amyloid cascade hypothesis...
Orlando: It’s Getting Hot around CDK5, Has the Field Noticed Yet?
In a sparsely attended slide presentation yesterday at the Neuroscience meeting, <strong>Inez Vincent</strong> of the University of Washington, Seattle, presented a feat no one seems to have pulled off before...
Orlando: It’s Not Acupuncture—LTP Is Going Parallel to Figure out Early Changes in AD
In the field’s current focus to understand what might go wrong at synapses early on in AD, measuring long-term potentiation has become a widely applied tool...
Current Filters
No filters selected