Accelerating the Cure for Alzheimer's Disease through Regenerative Medicine
Ready or Not: Stem Cell Therapies Poised to Enter Trials for Alzheimer’s Accelerating the Cure for Alzheimer's Disease through Regenerative Medicine
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Do High Blood Pressure Meds Reduce the Risk of ALS?
People who took prescription medications for hypertension were less likely than others to develop amyotrophic lateral sclerosis.
Society for Neuroscience Annual Meeting: A Haven for Basic Science
Basic preclinical discoveries keep meeting vibrant for neurodegenerative disease researchers from around the world
Society for Neuroscience Annual Meeting 2014
Society for Neuroscience Annual Meeting: A Haven for Basic Science Measuring Rapid Changes in Brain Aβ in Live Mice TREM2 Data Surprise at SfN Annual Meeting Meet GE180: A PET Ligand for Tracking Neuroinflammation? Exosomes: The FedEx of the Nervous Syste
Measuring Rapid Changes in Brain Aβ in Live Mice
A micro-immunoelectrode allows researchers measure Aβ levels in the interstitial fluid of mice every 30 seconds.
Does Amyloid Shrink Neurons, Shorten Their Fuses?
A study in a mouse model of Alzheimer’s disease proposes that degenerating neurons become more excitable because they lose dendrites.
Multiple Mutations Hasten ALS Onset, Suggests Genetic Study
Having variants in three, or even two, genes for amyotrophic lateral sclerosis brings on symptoms a decade earlier. This also happens in sporadic cases, bringing the very term into question, researchers say.
At High Doses, BACE1 Inhibitors Hinder Synaptic Plasticity in Mice
High doses of BACE1 inhibitors stymie synaptic activity in mice. Researchers recommend careful dosing in clinical trials.
TREM2 Data Surprise at SfN Annual Meeting
Protein touted as a peripheral monocyte receptor that worsens amyloid plaque pathology in transgenic mice.
Helper Drug Boosts Response to Riluzole in ALS Mice
Medication blocks molecular transporters that eject riluzole from the nervous system.
Meet GE180: A PET Ligand for Tracking Neuroinflammation?
After lighting up microglia in mouse models of AD, a tracer is headed for clinical trials.
CTAD Shows Alzheimer’s Field Trying to Reinvent Itself
A sense of change on all fronts pervaded the Clinical Trials on Alzheimer’s Disease conference. Scientists shared their early experiences of what works and what does not as they begin trials with newly defined cohorts, new diagnostic criteria, and new outcomes.
Clinical Trials on Alzheimer’s Disease 2014
CTAD Shows Alzheimer’s Field Trying to Reinvent Itself Rusty Unleashed: Forget Disease Modification, Go for Big Effect From Shared CAP, Secondary Prevention Trials Are Off and Running Immunotherapy I: Baby Steps, but No Breakthroughs Immunotherapy II: Act
Exosomes: The FedEx of the Nervous System?
Tiny secreted vesicles emerge as important players in communication between brain cells. Are they important in neurodegeneration?
TDP-43 Structure Reveals Two-Faced Amino End
The amino terminus toggles between a neatly folded nucleic acid-binding domain and a disorganized configuration that forms inclusions.
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