Meta-Analysis of 21 Years of Alzheimer's Fluid Biomarker Research
Study improves confidence in three core biomarkers and five emerging markers, most in cerebrospinal fluid and one in blood.
ALL NEWS
619 RESULTS
Sort By:
- Most Recent
- Most Commented
Does Uber APP Processing Drive Sporadic Alzheimer’s Disease?
In some people, Aβ40 in the cerebrospinal fluid correlates with plaque load in the brain.
Microglial Marker TREM2 Rises in Early Alzheimer’s and on Western Diet
Multiple studies link the amount and processing of this cell surface protein to inflammation and neurodegeneration, although what it does remains unclear.
Midlife Pep Does Not Curtail Alzheimer’s Biomarkers
Exercising the brain and body in middle age may not limit progression of Alzheimer’s pathology.
Can Antibody-Based PET Scans Pinpoint Aβ Oligomers in the Brain?
Researchers report the first successful use of this technology to detect soluble Aβ in the brains of Alzheimer’s mouse models.
Replication a Challenge in Quest for Alzheimer’s Blood Test
Researchers failed to confirm a high-profile, previous 10-lipid panel, but remain bullish on the potential of blood-based metabolites as biomarkers.
TREM2 Goes Up in Spinal Fluid in Early Alzheimer’s
TREM2 levels tracked with tau, but varied widely among patients and carriers of different mutations, leaving it unclear whether TREM2 helps or hurts.
Large Grant for Chronic Traumatic Encephalopathy Biomarker Study
Researchers will follow former football players at risk for the disorder to identify the best biomarkers and clinical criteria.
Countdown to Alzheimer’s: Can Fluid Biomarkers Predict Progression?
A small set of biomarkers in CSF and plasma may predict progression to Alzheimer’s within three years.
Biomarker Study in Down’s Syndrome Population May Yield Clues to AD
NIH announced a five-year study of Alzheimer’s biomarkers in middle-aged people with Down’s syndrome.
Scientists Eye Ocular Movements for Clues to Brain Pathology
Altered responses to visual stimuli could signify the extent of TDP-43 pathology in the brain, researchers predict.
Stressed Out: RNA-binding Protein Inhabits Granules in ALS, FTD
Meet RBM45. This RNA-binding protein and relatively new player in the ALS field associates with stress-induced structures in the cytoplasm and nucleus.
Neurofilament Light Chain: A Useful Marker for AD Progression?
The protein creeps up in the cerebrospinal fluid as the disease worsens.
Young ApoE4 Carriers Wander Off the ‘Grid’ — Early Predictor of Alzheimer’s?
Grid cells in the entorhinal cortex help with spatial navigation, and the cells’ function falters in young people at risk for AD.
Not Sexy but Oh-So-Important: Committee Blesses Way to Measure CSF Aβ
Moving toward a common standard for fluid-based Alzheimer’s diagnosis in routine clinical care, an intergovernmental metrology agency has certified a way of quantifying Aβ42.
Current Filters
- Biomarkers x