Taddei K, Yang D, Fisher C, Clarnette R, Hallmayer J, Barnetson R, Maller R, Brooks WS, Whyte S, Nicholson GA, Masters CL, Broe GA, Gandy SE, Martins RN. No association of presenilin-1 intronic polymorphism and Alzheimer's disease in Australia. Neurosci Lett. 1998 May 1;246(3):178-80. PubMed.
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Osaka City University Medical School
This reports essentially the negative result but is important for understanding presenilin-1 function. We should be aware of the large amount of sporadic cases besides familial cases.
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