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Home: Papers of the Week
Annotation


Adlard PA, Perreau VM, Pop V, Cotman CW. Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J Neurosci. 2005 Apr 27;25(17):4217-21. PubMed Abstract

Comments on Paper and Primary News
  Comment by:  Li-Huei Tsai
Submitted 2 May 2005  |  Permalink Posted 3 May 2005
  I recommend this paper

This is a very exciting study. It should be discussed together with the recent paper from the Sisodia group (Lazarov et al., 2005). Is the effect seen in the Lazarov et al. study due to exercise alone? Alternatively, do exercise and environment enrichment enhance learning and reduce Aβ via an overlapping mechanism?

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