How Does Excess Aβ Leave the Brain, How Does It Get In, And Can We Trap It Outside?

• 1 Comment

23 Jun 2003

1998;70:210-215. Abstract 18. Mackic JB, Bading J, Ghiso J, Walker L, Wisniewski T, Frangione B, Zlokovic BV.

Is Alzheimer's an Autoimmune Disease?

• 1 Comment

04 Dec 2003

of autoantibodies occur in control and AD serum. This may be changing now. A recent study of 18 AD

Are Glia Active Participants in Neurodegenerative Disease?

• 1 Comment

05 Dec 2005

Ben Barres led the first in a series of Alzforum discussions about the role of glial cells in Alzheimer’s and other neurodegenerative diseases. It has become trendy to say that glia are more than just glue, but in reality, science has not yet advanced sig

Leaky Blood-Brain Barrier a Harbinger of Alzheimer's?

• 1 Comment

30 Jan 2015

DCE-MRI scans of six healthy young people, 18 older folks who were cognitively normal, and 21 older adults

Intraneuronal Aβ: Was It APP All Along?

20 Jun 2011

peptides, induces neuronal apoptosis. J Biol Chem. 2002 May 3;277(18):15666-70. Abstract Leon WC, Canneva F,

A "Mitochondrial Cascade Hypothesis" for Sporadic Alzheimer's Disease

24 Sep 2004

I'll read your paper Hemachandra We looked at time course (two months, 12 months, 18 months, and 24

Slow Aβ; Clearance Is ApoE4’s Modus Operandi in Late-Onset AD

26 Jul 2011

number one genetic risk factor for late-onset Alzheimer’s disease (see AlzGene Top Results), yet 18 years

Adding Dynamics and Nuance to Alzheimer’s Staging

05 Jan 2012

18F-AV-45 (florbetapir F-18), an agent currently under consideration by the U.S. Food and Drug

Susceptibility Testing and Risk Assessment in Alzheimer Disease

01 May 2007

1999. 3: p. 65-70. Abstract 18. Sadovnick, A.D. and S. Lovestone, Ethical and legal issues: Genetic

Protein Folding and Neurodegeneration: Biophysics to the Rescue?

30 Apr 2003

molecule as a recent (Apr 18) Science paper mentions and the article by Charlie Glabe of 1994

BDNF and Alzheimer's Disease—What's the Connection?

25 Nov 2003

15;18(18):7336-50. Abstract Patterson SL, Abel T, Deuel TA, Martin KC, Rose JC, Kandel ER. Recombinant BDNF rescues

Isolation of Single Immunohistochemically Identified Whole Neuronal Cell Bodies from Post-Mortem Human Brain for Simultaneous Anlaysis of Multiple Gene Expression

27 Feb 1998

for G3PDH and now we use primers for 18s ribosomal RNA and the rate of positives is roughly 50 percent

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

20 Mar 1998

Marc Paradis led this live discussion on 20 March 1998. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Paper under Discussion: Li JH, Xu M, Zhou H. Ma J. and Potter H. Alzheimer presenilins in the n

Pin1, Tau and the Cell Cycle in Alzheimer Disease

03 Aug 1999

15;18:2801-2807. Abstract. 2. Campbell HD, Webb GC, Fountain S, Young IG. The human PIN1 peptidyl-prolyl cis/trans

Beta-Catenin and PS1

13 Aug 1999

Chris Weihl, with Bruce Yankner, Benjamin Wolozin, Eddie Koo, and Kenneth Kosik led this live discussion on 13 August 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion