Intracellular Aβ in Alzheimer's Disease

• 3 Comments

16 May 2000

Gunnar Gouras led this live discussion on 16 May 2000. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 16 May 2000.   Participants: Bruce Yankner, Huaxi Xu, Austin Ya

APP Family: Clues to Function in Health and AD

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29 Sep 2007

2007 Sep 15;120(Pt 18):3157-61. No abstract available. Abstract 0 NS: Text requested September 12. NS:

Meet New Players, Histone Deacetylase and Sirtuin—Will They Help the Cell Cycle, DNA Repair, and Gene Expression Break Into Alzheimerology’s Major League?

• 2 Comments

10 Feb 2009

but alters gene expression during aging. Cell. 2008 Nov 28;135(5):907-18. Abstract 0 Thursday,

Cerebrometabolic Deficiency in Alzheimer's Disease

• 2 Comments

22 Apr 2002

J Neural Transm 1998;(105):415-422. Abstract. 18. Sorbi S, Bird ED, Blass JP. Decreased pyruvate

Differential Neuronal Vulnerability

• 2 Comments

29 Jun 2005

dopamine neurons: implications for selective vulnerability in parkinsonism. Neurobiol Dis, 18, 19-31.

Targeting Tumor Necrosis Factor—A Therapeutic Strategy for AD

• 2 Comments

29 May 2008

affected the clinical status of patients with moderate to severe heart failure (18-20). Etanercept (Enbrel)

Probing PPARγ? Agonists: Could Diabetes Drugs Treat Alzheimer's Disease?

• 1 Comment

16 Dec 2002

with 30 patients. The study uses pioglitazone at 45 mg/day for 18 months. The primary outcome measures

Are Neurons Just Too Laissez-Faire about Repair?

• 1 Comment

24 Jul 2003

Thierry Nouspikel led this live discussion on 14 July 2003. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Dr. Thierry Nouspikel led this live discussion on 14 July 2003. Moderated by Dr

The Pathogen Hypothesis

• 1 Comment

24 Nov 2008

J Pathol. 2008 Sep 18. Abstract   References [1] Balin BJ, Gerard HC, Arking EJ, Appelt DM, Branigan PJ,

Not Dead Yet: Estrogen Deserves Another Chance

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28 Jan 2006

that leuprolide increased longevity in rats by 18 percent with 6 months of treatment. Mark Smith Craig,

Alzheimer's: A Triple Whammy. Why are So Many Neurodegenerative Diseases Single, Double, or Triple Amyloidoses?

• 1 Comment

22 Oct 2003

tauists and baptists finally shake hands? Trends Neurosci. 2002 Jan ;25(1):22-6. Abstract 18. Soto C.

Early Detection of Alzheimer Disease—A Virtual Town Hall Meeting

• 1 Comment

09 Jul 2008

disease. Q: Does anyone believe PET imaging, perhaps with F-18 amyloid tracers, will be clinically

The Neuroplasticity Theory of Alzheimer's Disease

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08 Apr 2002

J. Wesson Ashford led this live discussion on 8 April 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held Tuesday, 8 April 2002 Participants: John Wesson Ashford (W

Vascular Disease, Parkinson's, and Now Alzheimer's—Is Homocysteine the New All-Around Bad Guy?

• 1 Comment

12 May 2002

deficiency in AβPP-mutant mice in old age of your mice (about 18 months), but before amyloid deposition? Just

How the Other Half Lives—Or the What, How, and Where of the AβPP Intracellular Domain

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20 Sep 2002

Leissring: Kalpana White has done the most work in this area. Torroja et al., J Neurosci 19(18):7793 is one.