346257 RESULTS
RESEARCH NEWS 1999-09-15 Research News In today's Journal of Neuroscience, Vivian Budnik, Laura Torroja, and their colleagues at the University of Massachusetts, Amherst, and Brandeis University, Massachusetts, provide evidence that under normal circumstances, APP is a criti
RESEARCH NEWS 1999-09-13 Research News In the current Nature Cell Biology, Susan Lindquis and Jiang Ma of the Howard Hughes Institute at the University of Chicago report that they were able to produce abnormal prion protein (PrP) conformations from normal PrP, apparently by causi
RESEARCH NEWS 1999-08-31 Research News Douglas Smith and his colleagues at the University of Pennsylvania may have filled a gap in research on long-term, neurodegeneration sequelae of brain injuries by showing Aβ and tau production in an animal model of brain trauma. Their porcin
RESEARCH NEWS 1999-08-26 Research News If the inflammatory cytokine tumor necrosis factor α (TNF-α) is at work in Alzheimer's disease, it may not be relying on its well-described, directly apoptotic mechanism to cause problems, according to a report by Keith W. Kelley and hi
WEBINAR 1999-08-13 Chris Weihl, with Bruce Yankner, Benjamin Wolozin, Eddie Koo, and Kenneth Kosik led this live discussion on 13 August 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion
WEBINAR 1999-08-03 June Kinoshita, with Peter Davies, led this live discussion on 3 August 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Paper under discussion: Lu, Pei-Jung, Wulf, Gerburg, Zhou, Xiao Zhen, D
RESEARCH NEWS 1999-07-29 Research News In the August issue of Nature Neuroscience, Bruce Lamb and his associates at Case Western report that they have transferred complete copies of genes for mutant human APP and PS-1 into mice that subsequently produce high levels of Aβ and even
RESEARCH NEWS 1999-07-28 Research News Various recent studies have reported a link between head trauma and and an increased risk of Alzheimer's disease, but why this might be has been a matter of speculation. In this month’s Journal of Neurochemistry, Tracy McIntosh, Michell
RESEARCH NEWS 1999-07-07 Research News Findings reported in tomorrow’s issue of Nature raise the tantalizing possibility of using vaccination to prevent or ameliorate Alzheimer’s disease. In the study, by Dale Schenk and colleagues at Elan Pharmaceuticals, PDAPP transgenic mice w
RESEARCH NEWS 1999-06-23 Research News In tomorrow's issue of Nature, Jorge Ghiso and colleagues at New York University, and coworkers at the National Hospital for Neurology and Neurosurgery in London, report that they have found the gene mutation that produces the amyloid i
RESEARCH NEWS 1999-06-23 Research News In tomorrow’s issue of Nature (pp. 784-788), Kun Ping Lu of Harvard Medical School and colleagues report that an enzyme, prolyl isomerase Pin1, binds to phosphorylated tau from Alzheimer’s patients and restores tau’s ability to bind to micro
RESEARCH NEWS 1999-06-22 Research News Neurons taken from the brains of deceased Alzheimer's patients exhibit markers for apoptosis, but little is known about what induces the expression of apoptotic genes. In today’s proceedings of the National Academy of Science, a Univers
RESEARCH NEWS 1999-06-21 Research News Researchers studying the molecular basis of long-term potentiation (LTP) have typically focused on the role of NMDA glutamate receptor, but two papers published in the June 11 issue of Science elucidate the role of the other glutamate recept
RESEARCH NEWS 1999-06-17 Research News A 1997 study indicated that Alzheimer's patients who carried one or both alleles that code for the E4 form of apolipoprotein had more severe neurodegeneration than did patients who carried only alleles coding for the E3 form of the prot
INTERVIEWS 1999-06-15 Interviews ARF: Your work, although concentrating upon pathological states, seems applicable to both normal and disease-related biology. Is there a particular hypothesis which drives your work? KD: When you look at an AD brain at post-mortem, the most obv
No filters selected
