ALZANTIBODIES This monoclonal antibody recognizes a tau conformation that precedes the appearance of neurofibrillary tangles. Similar to monoclonal antibody MC-1, Alz-50 detects a discontinuous epitope that includes amino acids in tau’s N-terminal and third repeat regi
ALZANTIBODIES This monoclonal antibody was generated against paired helical filaments isolated from an Alzheimer’s brain. It recognizes a discontinuous epitope formed when tau folds in a way that brings together its N-terminal and third repeat regions. This tau conform
ALZANTIBODIES This monoclonal antibody, generated against paired helical filaments (PHFs) isolated from Alzheimer’s brains, recognizes tau phosphorylated at serine 202. CP-13 labels neurofibrillary tangles (NFTs), pretangles, neuropil threads, and dystrophic neurites i
ALZANTIBODIES This monoclonal antibody, generated against paired helical filaments isolated from the brains of Alzheimer’s patients, recognizes tau doubly phosphorylated at serines 396 and 404. Immuno-electron microscopy showed that the antibody binds to tau filaments