PAPER Kaplan L, Boss P

Depressive symptoms among spousal caregivers of institutionalized mates with Alzheimer's: boundary ambiguity and mastery as predictors.

Fam Process. 1999 Spring;38(1):85-103. PubMed.

PAPER Murphy MP, Hickman LJ, Eckman CB, Uljon SN, Wang R, Golde TE

gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length.

J Biol Chem. 1999 Apr 23;274(17):11914-23. PubMed.

PAPER Ye Y, Lukinova N, Fortini ME

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

Nature. 1999 Apr 8;398(6727):525-9. PubMed.

PAPER Struhl G, Greenwald I

Presenilin is required for activity and nuclear access of Notch in Drosophila.

Nature. 1999 Apr 8;398(6727):522-5. PubMed.

PAPER De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS, Schroeter EH, Schrijvers V, Wolfe MS, Ray WJ, Goate A, Kopan R

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.

Nature. 1999 Apr 8;398(6727):518-22. PubMed.

PAPER Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Nature. 1999 Apr 8;398(6727):513-7. PubMed.

PAPER Plummer JS, Cai C, Hays SJ, Gilmore JL, Emmerling MR, Michael W, Narasimhan LS, Watson MD, Wang K, Nath R, Evans LM, Jaen JC

Benzenesulfonamide derivatives of 2-substituted 4H-3,1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease.

Bioorg Med Chem Lett. 1999 Mar 22;9(6):815-20. PubMed.

PAPER Hardy J, Israël A

Alzheimer's disease. In search of gamma-secretase.

Nature. 1999 Apr 8;398(6727):466-7. PubMed.

PAPER Gökçora N, Atasever T, Karabacak NI, Vural G, Gücüyener K

Tc-99m HMPAO brain perfusion imaging in young Down's syndrome patients.

Brain Dev. 1999 Mar;21(2):107-12. PubMed.

PAPER Fernandez T, Yan WL, Hamburger S, Rapoport JL, Saunders AM, Schapiro M, Ginns EI, Sidransky E

Apolipoprotein E alleles in childhood-onset schizophrenia.

Am J Med Genet. 1999 Apr 16;88(2):211-3. PubMed.

PAPER Westermark G, Westermark P, Eizirik DL, Hellerström C, Fox N, Steiner DF, Andersson A

Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice.

Metabolism. 1999 Apr;48(4):448-54. PubMed.

PAPER Posner SF, Pedersen NL, Gatz M

Application of life table analysis to the onset of dementia in a genetically informative design.

Am J Med Genet. 1999 Apr 16;88(2):207-10. PubMed.

PAPER McIlroy SP, Vahidassr MD, Savage DA, Patterson CC, Lawson JT, Passmore AP

Risk of Alzheimer's disease is associated with a very low-density lipoprotein receptor genotype in Northern Ireland.

Am J Med Genet. 1999 Apr 16;88(2):140-4. PubMed.

PAPER Baum L, Chen L, Masliah E, Chan YS, Ng HK, Pang CP

Lipoprotein lipase mutations and Alzheimer's disease.

Am J Med Genet. 1999 Apr 16;88(2):136-9. PubMed.

PAPER Ki CS, Na DL, Kim JW, Kim HJ, Kim DK, Yoon BK

No association between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset Alzheimer's disease.

Am J Med Genet. 1999 Apr 16;88(2):113-5. PubMed.