340304 RESULTS
JOB 2024-11-01 Employer University of Leuven and VIB Principal Investigator Bart De Strooper Contact https://jobs.vib.be/j/93942/postdoctoral-researcher-to-develop-antisense-therapies-for-familial-alzheimers-disease Description The postdoctoral scientist will join the m
PAPER Hindam MO, Ahmed LA, El Sayed NS, Khattab M, Sallam NA
MUTATIONS MAPT 46010388 GRCh38/hg38 rs63751438 C T 44087754 GRCh37/hg19 rs63751438 C T Exon 10 Point, Missense Coding Enhances tau's ability to aggregate and seeding potency. Reduces tau's ability to promote microtubule assembly and bind to microtubules,
RESEARCH MODELS Summary These tau knockout rats were created through transcription activator-like effector nuclease (TALEN)-mediated targeting of exon 2 of the rat Mapt gene (Ayers, Lopez et al., 2024). Tau protein was undetectable in the brains of Cy23 rats by western b
MUTATIONS APOE 44908684 GRCh38/hg38 rs429358 T C 45411941 GRCh37/hg19 rs429358 T C Exon 4 Coding Strongest known risk factor for AD. Implicated in Aβ and tau pathologies, as well as in multiple other neuronal and non-neuronal functions. C130R Alzheimer's Disea
GRANT Friday, November 1, 2024- 3:15pm National Institutes of Health Tuesday, November 12, 2024 at 9:00 a.m. EST. Tuesday, November 12, 2024 at 3:00 p.m. EST. Both sessions will cover the same information. https://grants.nih.gov/grants/guide/notice-files/NOT-TW
GRANT Friday, November 1, 2024- 3:30pm National Institutes of Health Applications will be accepted that request a single, commercially available instrument or an integrated instrumentation system. The minimum award is $750,001. There is no upper limit on the co
RESEARCH MODELS Summary Tg12099 rats overexpress the 0N4R isoform of human tau with the P301S mutation linked to frontotemporal dementia. The MAPT transgene is driven by the rat Prnp promoter. Homozygous rats develop tau pathology, including neurofibrillary tangles, and
GRANT Friday, November 1, 2024- 3:45pm National Institutes of Health Applications will be accepted that request a single, commercially available instrument or an integrated instrumentation system. The minimum award is $50,000. There is no upper limit on the cos
GRANT Friday, November 1, 2024- 3:45pm National Institutes of Health Multiple due dates; see announcement. https://grants.nih.gov/grants/guide/pa-files/PAR-24-268.html 28 Jan 2027
GRANT Friday, November 1, 2024- 4:15pm National Institute of Neurological Disorders and Stroke Multiple due dates; see announcement. https://grants.nih.gov/grants/guide/pa-files/PAR-25-024.html 08 Jan 2028
GRANT Friday, November 1, 2024- 4:30pm National Institute of Neurological Disorders and Stroke Multiple due dates; see announcement. https://grants.nih.gov/grants/guide/pa-files/PAR-25-053.html 29 Jan 2027
GRANT Friday, November 1, 2024- 4:30pm National Institutes of Health Application budgets are limited to $100,000 in direct costs (excluding subcontract F&A) for one year and need to reflect the actual needs of the proposed project. Multiple due dates; see a
GRANT Friday, November 1, 2024- 5:00pm National Institute of Neurological Disorders and Stroke Application budgets need to reflect the actual needs of the proposed project; however, it is anticipated that most awards will be between $150,000-$800,000 direct cos
PAPER Mao C, Dong L, Li J, Huang X, Lei D, Wang J, Chu S, Liu C, Peng B, Cui L, Gao J
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