PAPER Main LR, Song YE, Lynn A, Laux RA, Miskimen KL, Osterman MD, Cuccaro ML, Ogrocki PK, Lerner AJ, Vance JM, Fuzzell D, Fuzzell SL, Hochstetler SD, Dorfsman DA, Caywood LJ, Prough MB, Adams LD, Clouse JE, Herington SD, Scott WK, Pericak-Vance MA, Haines JL
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340306 RESULTS
PAPER Thorns V, Mallory M, Hansen L, Masliah E
Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant.
Acta Neuropathol. 1997 Dec;94(6):539-48. PubMed.PAPER Takenouchi T, Hashimoto M, Hsu LJ, Mackowski B, Rockenstein E, Mallory M, Masliah E
Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein.
Mol Cell Neurosci. 2001 Jan;17(1):141-50. PubMed.PAPER Everall IP, Trillo-Pazos G, Bell C, Mallory M, Sanders V, Masliah E
Amelioration of neurotoxic effects of HIV envelope protein gp120 by fibroblast growth factor: a strategy for neuroprotection.
J Neuropathol Exp Neurol. 2001 Mar;60(3):293-301. PubMed.PAPER Everall IP, Bell C, Mallory M, Langford D, Adame A, Rockestein E, Masliah E
Lithium ameliorates HIV-gp120-mediated neurotoxicity.
Mol Cell Neurosci. 2002 Nov;21(3):493-501. PubMed.PAPER da Costa CA, Masliah E, Checler F
Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease.
J Biol Chem. 2003 Sep 26;278(39):37330-5. Epub 2003 Jul 16 PubMed.PAPER Langford D, Hurford R, Hashimoto M, Digicaylioglu M, Masliah E
Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.
BMC Neurosci. 2005 Feb 2;6:8. PubMed.PAPER Kuczenski R, Everall IP, Crews L, Adame A, Grant I, Masliah E
Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat.
Exp Neurol. 2007 Sep;207(1):42-51. Epub 2007 Jun 6 PubMed.PAPER Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, Gavina M, Pulze L, Giardino I, Pettoello-Mantovani M, D'Apolito M, Guido S, Masliah E, Spencer B, Quaratino S, Raia V, Ballabio A, Maiuri L
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.
Nat Cell Biol. 2010 Sep;12(9):863-75. Epub 2010 Aug 15 PubMed.PAPER Sunico CR, Nakamura T, Rockenstein E, Mante M, Adame A, Chan SF, Newmeyer TF, Masliah E, Nakanishi N, Lipton SA
S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease.
Mol Neurodegener. 2013 Aug 28;8:29. PubMed.PAPER Games D, Seubert P, Rockenstein E, Patrick C, Trejo M, Ubhi K, Ettle B, Ghassemiam M, Barbour R, Schenk D, Nuber S, Masliah E
Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synuclein.
Am J Pathol. 2013 Mar;182(3):940-53. Epub 2013 Jan 9 PubMed.PAPER Buxbaum JN, Roberts AJ, Adame A, Masliah E
Silencing of murine transthyretin and retinol binding protein genes has distinct and shared behavioral and neuropathologic effects.
Neuroscience. 2014 Sep 5;275:352-64. Epub 2014 Jun 21 PubMed.PAPER Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM
Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.
Cell Stem Cell. 2017 Mar 2;20(3):345-359.e5. Epub 2017 Jan 19 PubMed.PAPER He X, Yang W, Zeng Z, Wei Y, Gao J, Zhang B, Li L, Liu L, Wan Y, Zeng Q, Gong Z, Liu L, Zhang H, Li Y, Yang S, Hu T, Wu L, Masliah E, Huang S, Cao H
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
Cell Mol Immunol. 2020 Mar;17(3):283-299. Epub 2019 Jul 18 PubMed.Minzasolmin
THERAPEUTICS N-[(2R)-1-(1H-indol-3-yl)hexan-2-yl]-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide Neuropore Therapies, Inc. Novartis Pharmaceuticals Corporation UCB S.A. UCB0599 NPT200-11 Small Molecule alpha-synuclein In April 2021, UCB presented the results of
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