340483 RESULTS
ALZANTIBODIES Monoclonal antibody 1E5 reacts with the mouse P2Y12 receptor (P2Y12R). In initial testing, the antibody recognized its target on western blots of lysates from HEK293 cells that overexpress mouse P2Y12R. The antibody also stained microglia in mouse brains.
ALZANTIBODIES Monoclonal antibody 17D5 reacts with human CD33. In initial testing—on lysates of HEK293 cells that overexpressed myc-tagged human CD33 isoforms—it detected all three isoforms on Western blots and immunoprecipitated each isoform. The antibody was also sho
ALZANTIBODIES Monoclonal antibody 12C1 reacts with human CD33. In initial testing—on lysates of HEK293 cells that overexpressed myc-tagged human CD33 isoforms—it detected all three isoforms on Western blots and immunoprecipitated each isoform. The antibody was also sho
ALZANTIBODIES In initial testing on western blots, antibody 5A4 reacted with human TMEM119 overexpressed in HEK293 cells. Antibody 5A4 recognizes human TMEM119 overexpressed in HEK293 cells. Western blot of lysates of HEK293 cells transfected with empty vector (mock),
ALZANTIBODIES In initial testing, monoclonal antibody 9D10 recognized DAP12 endogenously expressed in the BV2 mouse microglial cell line, when used as a detection antibody for western blotting or a capture antibody for immunoprecipitation. The antibody also immunopreci
ALZANTIBODIES In initial testing, monoclonal antibody 14C2 recognized DAP12 endogenously expressed in the BV2 mouse microglial cell line, when used as a detection antibody for western blotting or a capture antibody for immunoprecipitation. The antibody also recognized
ALZANTIBODIES In initial testing, monoclonal antibody 4E12 recognized DAP12 endogenously expressed in the BV2 mouse microglial cell line, when used as a detection antibody for western blotting or a capture antibody for immunoprecipitation. The antibody also immunopreci
ALZANTIBODIES In initial testing, monoclonal antibody 1C8 recognized DAP12 endogenously expressed in the BV2 mouse microglial cell line, when used as a detection antibody for western blotting or a capture antibody for immunoprecipitation. The antibody also immunoprecip
ALZANTIBODIES Hyperphosphorylated tau polymerizes into paired helical filaments, which aggregate to form neurofibrillary tangles, one of the defining lesions of Alzheimer’s disease. AT8, which recognizes paired helical filament (PHF) tau, is one of the most widely used
ALZANTIBODIES This monoclonal antibody was generated against paired helical filaments isolated from an Alzheimer’s brain. It recognizes a discontinuous epitope formed when tau folds in a way that brings together its N-terminal and third repeat regions. This tau conform
ALZANTIBODIES This monoclonal antibody, generated against paired helical filaments (PHFs) isolated from Alzheimer’s brains, recognizes tau phosphorylated at serine 202. CP-13 labels neurofibrillary tangles (NFTs), pretangles, neuropil threads, and dystrophic neurites i
ALZANTIBODIES This monoclonal antibody, generated against paired helical filaments isolated from the brains of Alzheimer’s patients, recognizes tau doubly phosphorylated at serines 396 and 404. Immuno-electron microscopy showed that the antibody binds to tau filaments
ALZANTIBODIES This monoclonal antibody recognizes a tau conformation that precedes the appearance of neurofibrillary tangles. Similar to monoclonal antibody MC-1, Alz-50 detects a discontinuous epitope that includes amino acids in tau’s N-terminal and third repeat regi
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