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Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease.

Mol Pharmacol. 2000 Feb;57(2):409-17. PubMed.

PAPER Almkvist O, Fratiglioni L, Agüero-Torres H, Viitanen M, Bäckman L

Cognitive support at episodic encoding and retrieval: similar patterns of utilization in community-based samples of Alzheimer's disease and vascular dementia patients.

J Clin Exp Neuropsychol. 1999 Dec;21(6):816-30. PubMed.

PAPER Clare L, Wilson BA, Carter G, Breen K, Gosses A, Hodges JR

Intervening with everyday memory problems in dementia of Alzheimer type: an errorless learning approach.

J Clin Exp Neuropsychol. 2000 Feb;22(1):132-46. PubMed.

PAPER Lovell MA, Xie C, Markesbery WR

Decreased base excision repair and increased helicase activity in Alzheimer's disease brain.

Brain Res. 2000 Feb 7;855(1):116-23. PubMed.

PAPER Bassant MH, Poindessous-Jazat F, Schmidt BH

Sustained effect of metrifonate on cerebral glucose metabolism after immunolesion of basal forebrain cholinergic neurons in rats.

Eur J Pharmacol. 2000 Jan 10;387(2):151-62. PubMed.

PAPER Gabrieli JD, Vaidya CJ, Stone M, Francis WS, Thompson-Schill SL, Fleischman DA, Tinklenberg JR, Yesavage JA, Wilson RS

Convergent behavioral and neuropsychological evidence for a distinction between identification and production forms of repetition priming.

J Exp Psychol Gen. 1999 Dec;128(4):479-98. PubMed.

PAPER Skovronsky DM, Pijak DS, Doms RW, Lee VM

A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP.

Biochemistry. 2000 Feb 1;39(4):810-7. PubMed.

PAPER Matsumoto A, Itoh K, Matsumoto R

A novel carboxypeptidase B that processes native beta-amyloid precursor protein is present in human hippocampus.

Eur J Neurosci. 2000 Jan;12(1):227-38. PubMed.

PAPER Ho LH, Ratnaike RN, Zalewski PD

Involvement of intracellular labile zinc in suppression of DEVD-caspase activity in human neuroblastoma cells.

Biochem Biophys Res Commun. 2000 Feb 5;268(1):148-54. PubMed.

PAPER Kimberly WT, Xia W, Rahmati T, Wolfe MS, Selkoe DJ

The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation.

J Biol Chem. 2000 Feb 4;275(5):3173-8. PubMed.

PAPER Sester M, Feuerbach D, Frank R, Preckel T, Gutermann A, Burgert HG

The amyloid precursor-like protein 2 associates with the major histocompatibility complex class I molecule K(d).

J Biol Chem. 2000 Feb 4;275(5):3645-54. PubMed.

PAPER Shirotani K, Takahashi K, Araki W, Maruyama K, Tabira T

Mutational analysis of intrinsic regions of presenilin 2 that determine its endoproteolytic cleavage and pathological function.

J Biol Chem. 2000 Feb 4;275(5):3681-6. PubMed.

PAPER Anderton BH, Dayanandan R, Killick R, Lovestone S

Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?

Mol Med Today. 2000 Feb;6(2):54-9. PubMed.

PAPER Toro F, Lopera F, Ossa J, Madrigal L, Mira A, Díaz A, Parra S

[Detection of antibodies to beta-amyloid in carriers of E280A mutation in the presenilin-1 gene].

Rev Neurol. 1999 Dec 16-31;29(12):1104-7. PubMed.

PAPER Cabrera-Gómez JA, López-Saura P

[Recent advances in the treatment the nervous system disorders with interferon-alpha].

Rev Neurol. 1999 Dec 16-31;29(12):1225-35. PubMed.