Species: Mouse
Genes: APOE
Mutations: APOE R176C (ApoE2)
Modification: APOE: Knock-In
Disease Relevance: Alzheimer's Disease, Multiple Conditions
Strain Name: B6.129P2-Apoe^{tm1(APOE*2)Mae} N9
Genetic Background: 129 x C57BL/6; back-crossed to C57BL/6
Availability: Taconic: Stock# 1547-F and 1547-M

Summary

The APOE2 Targeted Replacement model is one line in a set of three APOE knock-in lines created by Nobuyo Maeda, Patrick Sullivan, and colleagues. APOE3 and APOE4 Targeted Replacement mice are also available. A detailed description of these lines can be found on the APOE3 Targeted Replacement page.

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References

Research Models Citations

1. APOE3 Targeted Replacement
2. APOE4 Targeted Replacement

External Citations

1. Taconic: Stock# 1547-F and 1547-M

Further Reading

No Available Further Reading