Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron. 2003 Jul 31;39(3):409-21. PubMed.

Recommends

Please login to recommend the paper.

Comments

No Available Comments

Make a Comment

To make a comment you must login or register.

This paper appears in the following:

Research Models

  1. 3xTg

News

  1. Synapses Sizzle in Limelight of Symposium Preceding Neuroscience Conference, Orlando: Day 2
  2. SfN: Where, How Does Intraneuronal Aβ Pack Its Punch? Part 1
  3. San Diego: Treating Forgetfulness—Triple Transgenics Provoke
  4. Can’t Close Spigot? Try Opening Drain: New Tack on Amyloid Degradation
  5. Research Brief: Glowing Glia Mark Disease Progression in AD Mice
  6. DC: New Neprilysin Methods Reduce Brain Aβ
  7. San Diego: Tweakers and Tweezers—Grappling with Novel Aβ Therapies
  8. Madrid: Beyond Aβ—Learning, Age, DNA Damage, and Pai-1
  9. Tackling Alzheimer’s from the Outside In
  10. Aβ and Phospho-tau: Strange Bedfellows Get Intimate at Synapses
  11. Philadelphia: The Enemy Within—Neurodegeneration From Intraneuronal Aβ
  12. Alzheimer: 100 Years and Beyond
  13. Transgenics Galore: Choking Apoptosis Rescues Triple AD Pathologies
  14. Mitochondria Sag Early in AD Mouse Model
  15. New Triple Transgenic Shows Mitochondrial Damage by Tau, Aβ
  16. New Retro: Mouse Gene Tweaks Both Aβ, Tau Pathology via GSK3
  17. Early Casualty, Neurogenesis Cripples Cognition in AD Mice
  18. Mistakes Prompt Retraction of Controversial Paper, and Publication Ban

Webinars

  1. Intraneuronal Aβ: Was It APP All Along?
  2. Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis

Research Timeline Event

  1. Triple and quintuple transgenic mice model faster disease course