Sirkis DW, Bonham LW, Aparicio RE, Geier EG, Ramos EM, Wang Q, Karydas A, Miller ZA, Miller BL, Coppola G, Yokoyama JS. Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression. Acta Neuropathol Commun. 2016 Sep 2;4(1):98. PubMed.

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Mutations

  1. TREM2 S16F
  2. TREM2 V27M
  3. TREM2 S31F
  4. TREM2 R47C
  5. TREM2 A130S
  6. TREM2 S162R
  7. TREM2 A196T
  8. TREM2 D87N
  9. TREM2 A28V
  10. TREM2 R136Q
  11. TREM2 R136W
  12. TREM2 E151K
  13. TREM2 E202D
  14. TREM2 H215Q
  15. TREM2 T223I