Andersson ME, Sjölander A, Andreasen N, Minthon L, Hansson O, Bogdanovic N, Jern C, Jood K, Wallin A, Blennow K, Zetterberg H. Kinesin gene variability may affect tau phosphorylation in early Alzheimer's disease. Int J Mol Med. 2007 Aug;20(2):233-9. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ42 (CSF) |
AD (585) |
457 ± 6.6† pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
Aβ42 (CSF) |
CTRL- CNC (161) |
712 ± 14.8† pg/mL |
ELISA; Innotest; Innogenetics |
|
tau-p181 (CSF) |
AD (567) |
81.4 ± 1.4† ng/L |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
tau-p181 (CSF) |
CTRL- CNC (131) |
62.1 ± 1.6† ng/L |
ELISA; Innotest; Innogenetics |
|
tau-total (CSF) |
AD (599) |
668 ± 12.8† ng/L |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
tau-total (CSF) |
CTRL- CNC (161) |
351 ± 12.2† ng/L |
ELISA; Innotest; Innogenetics |
† Mean ± SEM
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