Lin YT, Cheng JT, Yao YC, Juo, Lo YK, Lin CH, Ger LP, Lu PJ. Increased total TAU but not amyloid-beta(42) in cerebrospinal fluid correlates with short-term memory impairment in Alzheimer's disease. J Alzheimers Dis. 2009;18(4):907-18. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (28) |
211.6 ± 19.7† pg/mL |
ELISA; Other/Not Specified; Biosource |
McKhann et al., 1984 |
| Aβ42 (CSF) |
CTRL- CNC (21) |
371.2 ± 35.4† pg/mL |
ELISA; Other/Not Specified; Biosource |
|
| tau-total (CSF) |
AD (28) |
399 ± 41.2† pg/mL |
ELISA; Other/Not Specified; Biosource |
McKhann et al., 1984 |
| tau-total (CSF) |
CTRL- CNC (21) |
154 ± 9.9† pg/mL |
ELISA; Other/Not Specified; Biosource |
† Mean ± SEM
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