Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem. 2003 Aug;86(3):582-90. PubMed.

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    • User Profile Image Todd E. Golde
      Goizueta Institute @ Emory Brain Health
    • Posted:

    This could be the best model for studying AD like tauopathies, as these mice develop tangles without mutations. The finding that this only occurs when mouse tau is KO'ed is very interesting....

    View all comments by Todd E. Golde

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