Yang Y, Keene CD, Peskind ER, Galasko DR, Hu SC, Cudaback E, Wilson AM, Li G, Yu CE, Montine KS, Zhang J, Baird GS, Hyman BT, Montine TJ. Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease. J Neuropathol Exp Neurol. 2015 Jul;74(7):672-87. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- PD vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- PD vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
- PD vs AD : tau-total (CSF)
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ42 (CSF) |
AD (27) |
201 ± 18 pg/mL |
xMAP; AlzBio3; Fujirebio |
McKhann et al., 2011 |
Aβ42 (CSF) |
CTRL- CNC (23) |
311 ± 29 pg/mL |
xMAP; AlzBio3; Fujirebio |
|
Aβ42 (CSF) |
PD (24) |
348 ± 22 pg/mL |
xMAP; AlzBio3; Fujirebio |
|
tau-p181 (CSF) |
AD (27) |
69 ± 7 pg/mL |
xMAP; AlzBio3; Fujirebio |
McKhann et al., 2011 |
tau-p181 (CSF) |
CTRL- CNC (23) |
39 ± 4 pg/mL |
xMAP; AlzBio3; Fujirebio |
|
tau-p181 (CSF) |
PD (24) |
27 ± 2 pg/mL |
xMAP; AlzBio3; Fujirebio |
|
tau-total (CSF) |
AD (27) |
101 ± 7 pg/mL |
xMAP; AlzBio3; Fujirebio |
McKhann et al., 2011 |
tau-total (CSF) |
CTRL- CNC (23) |
57 ± 4 pg/mL |
xMAP; AlzBio3; Fujirebio |
|
tau-total (CSF) |
PD (24) |
39 ± 4 pg/mL |
xMAP; AlzBio3; Fujirebio |
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