Palumbo B, Siepi D, Sabalich I, Tranfaglia C, Parnetti L. Cerebrospinal fluid neuron-specific enolase: a further marker of Alzheimer's disease?. Funct Neurol. 2008 Apr-Jun;23(2):93-6. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ42
(CSF)		 AD
(76)		 413.8 ± 163.7
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
Aβ42
(CSF)		 CTRL-
CNC
(30)		 914.4 ± 277.1
pg/mL		 ELISA;
Innotest;
Innogenetics
Aβ42
(CSF)		 DLB
(20)		 477.1 ± 225.7
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith, 2006
Aβ42
(CSF)		 FTD
(28)		 497.1 ± 221.9
pg/mL		 ELISA;
Innotest;
Innogenetics		 1994
NSE
(CSF)		 AD
(76)		 15.1 ± 9.9
ng/mL		 Radio Immunoassay;
Other/Not Specified;
CIS Bio International S.A.		 McKhann et al., 1984
NSE
(CSF)		 CTRL-
CNC
(30)		 8.3 ± 3.5
ng/mL		 Radio Immunoassay;
Other/Not Specified;
CIS Bio International S.A.
tau-total
(CSF)		 AD
(76)		 607.9 ± 372.3
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKhann et al., 1984
tau-total
(CSF)		 CTRL-
CNC
(30)		 176.6 ± 43.9
pg/mL		 ELISA;
Innotest;
Innogenetics
tau-total
(CSF)		 DLB
(20)		 472.3 ± 357.7
pg/mL		 ELISA;
Innotest;
Innogenetics		 McKeith, 2006
tau-total
(CSF)		 FTD
(28)		 541.76 ± 362.8
pg/mL		 ELISA;
Innotest;
Innogenetics		 1994

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ42 (CSF)
  2. CTRL vs AD : Aβ42 (CSF)
  3. DLB vs AD : Aβ42 (CSF)
  4. FTD vs AD : Aβ42 (CSF)
  5. AD vs CTRL : NSE (CSF)
  6. CTRL vs AD : NSE (CSF)
  7. AD vs CTRL : tau-total (CSF)
  8. CTRL vs AD : tau-total (CSF)
  9. DLB vs AD : tau-total (CSF)
  10. FTD vs AD : tau-total (CSF)