Jensen M, Schröder J, Blomberg M, Engvall B, Pantel J, Ida N, Basun H, Wahlund LO, Werle E, Jauss M, Beyreuther K, Lannfelt L, Hartmann T. Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression. Ann Neurol. 1999 Apr;45(4):504-11. PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)		 Cohort
(N)		 Measurement
Mean ± SD		 Method;
Assay Name;
Manufacturer		 Diagnostic
Criteria
Aβ40
(CSF)		 AD
(80)		 1922 ± 547
pM		 ELISA;
Other/Not Specified;
In-house		 McKhann et al., 1984
Aβ40
(CSF)		 CTRL-
CNC
(24)		 2311 ± 546
pM		 ELISA;
Other/Not Specified;
In-house
Aβ40
(CSF)		 DEP
(15)		 1895 ± 662
pM		 ELISA;
Other/Not Specified;
In-house		 1993
Aβ42
(CSF)		 AD
(80)		 119 ± 63
pM		 ELISA;
Other/Not Specified;
In-house		 McKhann et al., 1984
Aβ42
(CSF)		 CTRL-
CNC
(24)		 74 ± 30
pM		 ELISA;
Other/Not Specified;
In-house
Aβ42
(CSF)		 DEP
(15)		 180 ± 95
pM		 ELISA;
Other/Not Specified;
In-house		 1993

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This paper appears in the following:

AlzBiomarker

  1. AD vs CTRL : Aβ40 (CSF)
  2. CTRL vs AD : Aβ40 (CSF)
  3. DEP vs AD : Aβ40 (CSF)
  4. AD vs CTRL : Aβ42 (CSF)
  5. CTRL vs AD : Aβ42 (CSF)
  6. DEP vs AD : Aβ42 (CSF)