Maruyama M, Arai H, Sugita M, Tanji H, Higuchi M, Okamura N, Matsui T, Higuchi S, Matsushita S, Yoshida H, Sasaki H. Cerebrospinal fluid amyloid beta(1-42) levels in the mild cognitive impairment stage of Alzheimer's disease. Exp Neurol. 2001 Dec;172(2):433-6. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
---|---|---|---|---|
Aβ42 (CSF) |
AD (54) |
397.6 ± 164.1 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
Aβ42 (CSF) |
CTRL- Other Controls (15) |
563.3 ± 191 pg/mL |
ELISA; Innotest; Innogenetics |
|
tau-total (CSF) |
AD (54) |
638.7 ± 321.5 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
tau-total (CSF) |
CTRL- Other Controls (15) |
181.9 ± 101.5 pg/mL |
ELISA; Innotest; Innogenetics |
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