Mruthinti S, Buccafusco JJ, Hill WD, Waller JL, Jackson TW, Zamrini EY, Schade RF. Autoimmunity in Alzheimer's disease: increased levels of circulating IgGs binding Abeta and RAGE peptides. Neurobiol Aging. 2004 Sep;25(8):1023-32. PubMed.

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  1. We have noted increased level of intracellular IL-4 and IL-10 in CD4 T cells of patients with AD. We speculate that increased cytokines are compensatory to impaired cellular immunity (Mruthinti et al., 2004).

    References:

    Mruthinti S, Buccafusco JJ, Hill WD, Waller JL, Jackson TW, Zamrini EY, Schade RF. Autoimmunity in Alzheimer's disease: increased levels of circulating IgGs binding Abeta and RAGE peptides. Neurobiol Aging. 2004 Sep;25(8):1023-32. PubMed.

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