Santos AN, Ewers M, Minthon L, Simm A, Silber RE, Blennow K, Prvulovic D, Hansson O, Hampel H. Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease. J Alzheimers Dis. 2012;29(1):171-6. PubMed.
AlzBiomarker Database
Meta-Analysis
- AD vs CTRL : Aβ42 (CSF)
- CTRL vs AD : Aβ42 (CSF)
- AD vs CTRL : tau-p181 (CSF)
- CTRL vs AD : tau-p181 (CSF)
- AD vs CTRL : tau-total (CSF)
- CTRL vs AD : tau-total (CSF)
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (14) |
262.1 ± 42.1 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984; 1986 |
| Aβ42 (CSF) |
CTRL- Other Controls (12) |
685 ± 175.2 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-p181 (CSF) |
AD (14) |
122.2 ± 28.4 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984; 1986 |
| tau-p181 (CSF) |
CTRL- Other Controls (12) |
40.4 ± 10.8 pg/mL |
ELISA; Innotest; Innogenetics |
|
| tau-total (CSF) |
AD (14) |
942.8 ± 216.5 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984; 1986 |
| tau-total (CSF) |
CTRL- Other Controls (12) |
253.3 ± 77.1 pg/mL |
ELISA; Innotest; Innogenetics |
Recommends
Please login to recommend the paper.
Comments
No Available Comments
Make a Comment
To make a comment you must login or register.