Clonality: polyclonal
Host: Rabbit
Source: αAβC42
J. Buxbaum, Mt. Sinai School of Medicine, NewYork, NY
Paper
References:
Hashimoto, 2010
Lord, 2009
Näslund, 2000
Formulation: serum
Reactivity:
Reacts in: Human, Mouse

Immunogen/Epitope

immunogen = peptide corresponding to the 6 Cterminal
residues of Abx-42 and containing N-terminal cysteine
residues, coupled to KLH

Specificity

recognizes amyloid-beta x-42

Comments / Questions

No Available Comments

Make a comment or submit a question

To make a comment you must login or register.

References

Paper Citations

1. Hashimoto M, Bogdanovic N, Volkmann I, Aoki M, Winblad B, Tjernberg LO. Analysis of microdissected human neurons by a sensitive ELISA reveals a correlation between elevated intracellular concentrations of Abeta42 and Alzheimer's disease neuropathology. Acta Neuropathol. 2010 May;119(5):543-54. PubMed.
2. Lord A, Gumucio A, Englund H, Sehlin D, Sundquist VS, Söderberg L, Möller C, Gellerfors P, Lannfelt L, Pettersson FE, Nilsson LN. An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease. Neurobiol Dis. 2009 Dec;36(3):425-34. PubMed.
3. Näslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, Buxbaum JD. Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline. JAMA. 2000 Mar 22-29;283(12):1571-7. PubMed.

External Citations

1. J. Buxbaum
2. Paper

Further Reading

No Available Further Reading