PD Studies Suggest Motor Cortex as Treatment Target
A spinal cord procedure less invasive than those that deliver epidural anesthesia can restore locomotion in two rodent models of Parkinson disease...
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Deep-Brain Stimulation: Decade of Surgical Relief, Not Just for PD
In this series, ARF takes stock of deep-brain stimulation after more than a decade of life-altering procedures...
PD Studies Highlight Deep Brain Stimulation, New Role for α-Synuclein
Parkinson disease researchers can ring in the new year with a pair of high-profile studies...
AD Research Participation: Informed Consent Complicates Trials, Part 1
Compared with decades past, the clinical pipeline for investigational Alzheimer disease therapies is ready to burst...
The Plot Thickens: The Complicated Relationship of Tau and Aβ
Researchers are finding that Aβ and tau revolve more closely around each other than they had thought...
DIAN Forms Pharma Consortium, Submits Treatment Trial Grant
In their quest to offer treatment trials to families with autosomal-dominant AD, the scientists driving the DIAN have cleared the next hurdles...
As ADNI Turns Four, $64 Million Data Start Rolling In
The Alzheimer Disease Neuroimaging Initiative (ADNI) is the largest AD study the National Institutes of Health have ever funded...
Honolulu: Neuroregeneration Taps Glia, Neurotrophins
New data from several independent studies suggest using neural stem cells to patch wide swaths of failing brain circuitry in AD may have a fighting chance...
New Theory for Some ALS Cases—SOD1 Plugs Cell Power Plants
The misfolded enzyme that causes some kinds of amyotrophic lateral sclerosis poisons motor neurons by plugging up pores in their mitochondria...
Parkinson’s: Thinking Outside the Brain’s Black Box
When an anatomist first proposed that Parkinson’s disease begins in the gut, then slowly makes its way to the brain, his idea might have sounded like fiction...
NAPA Advisory Council Named, Seeks Input From Researchers
Kathleen Sibelius announced the 12 non-federal members who will serve on the Advisory Council on Alzheimer’s Research, Care, and Services...
Outlook for PPARγ Agonists Not So Rosi
Hope that thiazolidinedione agonists of PPARγ will prove beneficial for Alzheimer's patients (see <a href="/res/for/journal/galea/default.asp">ARF recent live discussion</a>) may be tempered slightly by a report...
PPARγ Partner PGC-1α Linked to Huntington Disease-Like Symptoms
PPARγ has received a lot of attention from neuroscientists lately. Now, ablation of one of its partners, PGC-1α, has been found to cause...
Insulin Resistance Correlates With Plaque, But Not Tangle, Pathology
Having diabetes seems to drive up risk for dementia, including Alzheimer disease, but the jury has been out as to how this occurs...
Research Brief: After Weight-Loss Surgery, AD-Related Proteins Drop
Scientists report that people who undergo gastric bypass surgery to lose weight have lower levels of several AD-related proteins in their blood six months later...
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