Vascular Disease, Parkinson's, and Now Alzheimer's—Is Homocysteine the New All-Around Bad Guy?

• 1 Comment

12 May 2002

Mark Mattson led this live discussion on 30 April 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live Discussion held 30 April 2002. Participants: Mark Mattson, Anthony White, Andr

Neural Stem Cells to the Rescue—Can Neuroreplacement Ever Become a Treatment for Alzheimer's?

09 Jul 2002

Kiminobu Sugaya led this live discussion on 9 July 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 9 July 2002, 12 noon-1 p.m EST with Kiminobu Sugaya. Particip

Alzheimer Genes in Cortical Development: How Do Their Prenatal Functions Relate to Dementia?

12 Jul 2002

Jie Shen led this live discussion on 12 July 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 12 July 2002, 12 noon-1 p.m EST with Jie Shen. Participants: Jie Sh

From Here to There: AβPP as an Axonal Transport Receptor—How Could This Explain Neurodegeneration in AD?

15 Jul 2002

Larry Goldstein led this live discussion on 15 July 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.   See a follow-up live discussion background text: Axonal Transport Hypothesis Moves On to Im

The Cell Cycle and Alzheimer’s Disease—Let's Unite for Division!

• 6 Comments

07 Aug 2002

Inez Vincent led this live discussion on 7 August 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. See diagram from Inez Vincent Transcript: Live discussion held 20 May 2002 at 12 noon. Particip

β Amyloid Degradation: The Forgotten Half of Alzheimer's Disease

• 7 Comments

12 Sep 2002

Malcolm Leissring and Wesley Farris led this live discussion on 12 September 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 12 September 2002 with Wesley Farri

How the Other Half Lives—Or the What, How, and Where of the AβPP Intracellular Domain

• 1 Comment

20 Sep 2002

Frank LaFerla led this live discussion on 20 September 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 20 September 2002, featuring Frank LaFerla of the Univers

Will Probing Flies and Worms Bear Fruit in the Search for New Genes Involved in Alzheimer's?

29 Oct 2002

Mel Feany led this live discussion on 29 October 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 29 October 2002, featuring Mel Feany of Brigham and Women'

Cholesterol and Alzheimer's—Charging Fast But Still at a Distance from Solid Answers

• 3 Comments

19 Nov 2002

Tobias Hartmann led this live discussion on 19 November 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 19 November 2002. Led by Tobias Hartmann of the Universi

Intraneuronal Aβ Accumulation—More Evidence, Less Controversy?

• 1 Comment

26 Nov 2002

Gunnar Gouras led this live discussion on 26 November 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 26 November 2002 featuring Gunnar Gouras Participants: Gun

CAA: We All Know It's There, But Just What Is It Doing in Alzheimer's?

12 Mar 2003

Steven Greenberg and Mathias Jucker led this live discussion on 12 March 2003. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript unavailable. Background Text By Steven Greenberg and Mathias

RNAi in Neurodegenerative Diseases—What's the Therapeutic Potential?

18 Mar 2003

By Zuoshang Xu, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 Zuoshang Xu led this live discussion on 18 March 2003. Readers are invited to submit additional comments by using our Co

Cholinergic Plasticity in Hippocampus of Individuals with Mild Cognitive Impairment: Correlation with Alzheimer's Neuropathology

19 May 2003

This Live Journal Discussion is the first in a series of upcoming discussions of selected articles in the Journal of Alzheimer's Disease, which is making the full text (.pdf) of these papers available to Alzforum for this purpose. Paper du Jour: Ikon

Axonal Transport Hypothesis Moves On to Implicate Presenilin

• 1 Comment

17 Jun 2003

This live discussion is an update of last year's initial Live Discussion of axonal transport as an underlying factor in neurodegeneration. Jorge Busciglio and Scott Brady led this live discussion on 17 June 2003. Readers are invited to submit additio

How Does Excess Aβ Leave the Brain, How Does It Get In, And Can We Trap It Outside?

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23 Jun 2003

Berislav Zlokovic led this live discussion on 23 June 2003. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Berislav Zlokovic, University of Rochester, led this live discussion on 23 June