Treating Before Symptoms—ADCS Invites Ideas for Clinical Trials in Very Early AD

09 Jun 2010

measure as a primary outcome in this population. Notably, a recent paper demonstrates the utility of

Weeding Mendel’s Garden: Can We Hoe Dubious Genetic Associations?

03 Aug 2012

original papers and understand enough to know whether you can trust it. Marc Cruts: I believe that it is

A "Mitochondrial Cascade Hypothesis" for Sporadic Alzheimer's Disease

24 Sep 2004

nuclear gene expression will also prove informative; Hemachandra had a wonderful paper a few months ago

Alzheimer Disease—The Fragile X Syndrome Connection

23 Feb 2007

characterized by synaptic pathology and as exemplified by a paper in this month’s PLoS, the two may have

Slow Aβ; Clearance Is ApoE4’s Modus Operandi in Late-Onset AD

26 Jul 2011

generously granted free access to Castellano et al. for Alzforum readers. For a brief summary of the paper

Can Network Analysis Identify Pathological Pathways in Alzheimer’s

04 Jun 2013

thank Cell Press for giving Alzforum readers temporary free access to these papers: Zhang B, Gaiteri C,

Susceptibility Testing and Risk Assessment in Alzheimer Disease

01 May 2007

the topic of a forthcoming paper. Our preliminary analyses suggest that participants found to be at

Protein Folding and Neurodegeneration: Biophysics to the Rescue?

30 Apr 2003

molecule as a recent (Apr 18) Science paper mentions and the article by Charlie Glabe of 1994

BDNF and Alzheimer's Disease—What's the Connection?

25 Nov 2003

mechanisms driving this (we elaborated on this in our TINS paper last year; see Cotman and Berchtold, 2002).

Deficiency of Presenilin 1 Inhibits the Normal Cleavage of the Transmembrane Domain of Amyloid Precursor Protein

30 Jan 1998

to submit additional comments by using our Comments form at the bottom of the page. Paper Under

Isolation of Single Immunohistochemically Identified Whole Neuronal Cell Bodies from Post-Mortem Human Brain for Simultaneous Anlaysis of Multiple Gene Expression

27 Feb 1998

additional comments by using our Comments form at the bottom of the page. Paper Under Discussion: Cheetham

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

20 Mar 1998

comments by using our Comments form at the bottom of the page. Paper under Discussion: Li JH, Xu M, Zhou H.

Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down's Syndrome Patients

28 May 1998

Leeuwen: Yes, we think. As indicated in the Science paper ref.30 we have found similar events outside the

Apoptosis in Alzheimer Disease

24 Mar 1999

Perry: Is that what you said in your earlier papers? Carl Cotman: Yes Carl Cotman: Cummings- get back to

Pin1, Tau and the Cell Cycle in Alzheimer Disease

03 Aug 1999

to submit additional comments by using our Comments form at the bottom of the page.   Paper under