Beta-Catenin and PS1

13 Aug 1999

signalling. I thought that we might open the forum with a brief discussion about why papers have demonstrated

Protofibrillar Aβ in Alzheimer's Disease

17 Feb 2000

Dean? William Klein: Let me start by saying how much I enjoyed the paper by Dean et al. A good read.

Generation of an Apoptotic Intracellular Peptide by γ-secretase Cleavage of Alzheimer's β-amyloid Precursor Protein

20 Sep 2000

postmortem? Luciano: We reported in our JAD paper the isolation of AID-like peptides from the brains of normal

New Theories of Presenilin Function

12 Dec 2000

Dr.Thinakaran, firstly we should show what is the problem between our paper and Sato's paper (Nature Cell

The Role of ApoE in Alzheimer's Disease: An Alternative View

11 Dec 2001

Mesulam, 1999; Lue et al, 1999; Koudinov et al, 2001.) Also, a recent paper by a Scottish group (White, et

Neural Stem Cells to the Rescue—Can Neuroreplacement Ever Become a Treatment for Alzheimer's?

09 Jul 2002

a longer answer; check our papers and I will talk with you about that answer later. Bye. Kiminobu Sugaya:

Alzheimer Genes in Cortical Development: How Do Their Prenatal Functions Relate to Dementia?

12 Jul 2002

Hiroko, Marc is not the only one who has done work on this. I believe there are over 30 papers on the

From Here to There: AβPP as an Axonal Transport Receptor—How Could This Explain Neurodegeneration in AD?

15 Jul 2002

Larry, how do you connect your cytoplasmic events with nuclear events? (See related paper.) To be more

Will Probing Flies and Worms Bear Fruit in the Search for New Genes Involved in Alzheimer's?

29 Oct 2002

Orlando, I suppose... I have read your recent paper, Chris, and am excited to have you join us. Chris Link

RNAi in Neurodegenerative Diseases—What's the Therapeutic Potential?

18 Mar 2003

years ago there was a Nature Cell Biology paper showing knockout phenotypes with RNAi very early in

Cholinergic Plasticity in Hippocampus of Individuals with Mild Cognitive Impairment: Correlation with Alzheimer's Neuropathology

19 May 2003

in the Journal of Alzheimer's Disease, which is making the full text (.pdf) of these papers

Therapeutic Nihilism: Widespread Yet Passé? AD Acetylcholinesterase Inhibitors Are Better Than Their Reputation

14 Oct 2003

papers details potential benefits of the cholinesterase inhibitors, with the data for each being

Novel Substrates for BACE1 Beg the Question: What's the Biological Function of β-Secretase?

17 Dec 2003

not all present here today have had a chance to read your latest paper yet. Everyone, while Stefan is

Clioquinol Trial Postmortem: Does Blocking Metal-Aβ Interactions Work?

15 Jan 2004

Neurology paper we reported that the side effects were not remarkable. Previously, clioquinol (CQ) was

Stem Cell Therapies for Neurodegenerative Disease: How Should We Push Ahead?

30 Mar 2004

Rao, are you as depressed as I am about those two Nature papers that just came out showing a failure of