β Amyloid Degradation: The Forgotten Half of Alzheimer's Disease

• 7 Comments

12 Sep 2002

thanks.. I was just looking at an older Selkoe paper concluding IDE mostly works extracellularly. Gabrielle

The Cell Cycle and Alzheimer’s Disease—Let's Unite for Division!

• 6 Comments

07 Aug 2002

die but without forming NFT. (paper under review). Craig Atwood: Inez, for amyloid in Niemann-Pick

From Here to There: AβPP as an Axonal Transport Receptor—How Could This Explain Neurodegeneration in AD?

15 Jul 2002

Larry, how do you connect your cytoplasmic events with nuclear events? (See related paper.) To be more

Alzheimer Genes in Cortical Development: How Do Their Prenatal Functions Relate to Dementia?

12 Jul 2002

Hiroko, Marc is not the only one who has done work on this. I believe there are over 30 papers on the

Neural Stem Cells to the Rescue—Can Neuroreplacement Ever Become a Treatment for Alzheimer's?

09 Jul 2002

a longer answer; check our papers and I will talk with you about that answer later. Bye. Kiminobu Sugaya:

Vascular Disease, Parkinson's, and Now Alzheimer's—Is Homocysteine the New All-Around Bad Guy?

• 1 Comment

12 May 2002

cardiovascular disease. Every paper has a different angle. Mark Mattson: {enters} Hello, did everyone take their

The Neuroplasticity Theory of Alzheimer's Disease

• 1 Comment

08 Apr 2002

paper. Pascale Lacor: Gabrielle: Steve Paul's and Dave Holtzman's groups have a paper today

From Epidemiology to Therapeutic Trials with Anti-inflammatory Drugs in Alzheimer's Disease: The Role of NSAIDs and Cyclooxygenase on Beta-amyloidosis and Clinical Dementia

• 4 Comments

20 Mar 2002

Pasinetti: We recently submitted a paper suggesting that the overexpression in the brain of COX-2 transgenic

Alzheimer Immunotherapy Trial Grounded: Time to Reassess Safety and Vaccine Design

• 3 Comments

05 Mar 2002

Frangione, New York University Comment and ARF Exchange on paper by Frenkel et al. Transcript: Live

Hemochromatosis as a Factor in AD

• 1 Comment

22 Jan 2002

discussion paper "Previous attempts to treat AD with antioxidants or iron chelation have been

Picking up the Pieces of Parkin

• 1 Comment

17 Jan 2002

described in the Farrer paper (Farrer et al., 2001) is a partially active mutant as described in our Nature

The Role of ApoE in Alzheimer's Disease: An Alternative View

11 Dec 2001

Mesulam, 1999; Lue et al, 1999; Koudinov et al, 2001.) Also, a recent paper by a Scottish group (White, et

Gonadal Hormone Withdrawal, Apoptosis, and Generation of Beta Amyloid Peptide: A Vicious Cycle of Amyloidogenesis and Neurotoxicity in Alzheimer's Disease

• 5 Comments

05 Dec 2001

gonadotrophin levels under any circumstances. A paper on ovariectomy effects on Ab load in transgenic mice is in

Calcium Signaling Deficit in the Origin of Alzheimer's Disease

• 8 Comments

07 Sep 2001

Live discussion and panel of participants scheduled for 7 September 2001.     Summary: "Ca2+ deficit" hypothesis Summary: "Natural origin" hypothesis for plaques and tangles The live chat and panel of participants scheduled for 7 Septe

Nomenclature Discussion

• 5 Comments

15 Aug 2001

pre-medline is out! June: I can live with that. Colin Masters: Just review the last hundred papers. Msmith: