New Theories of Presenilin Function

12 Dec 2000

Dr.Thinakaran, firstly we should show what is the problem between our paper and Sato's paper (Nature Cell

Generation of an Apoptotic Intracellular Peptide by γ-secretase Cleavage of Alzheimer's β-amyloid Precursor Protein

20 Sep 2000

postmortem? Luciano: We reported in our JAD paper the isolation of AID-like peptides from the brains of normal

Intracellular Aβ in Alzheimer's Disease

• 3 Comments

16 May 2000

Gunnar Gouras led this live discussion on 16 May 2000. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 16 May 2000.   Participants: Bruce Yankner, Huaxi Xu, Austin Ya

Protofibrillar Aβ in Alzheimer's Disease

17 Feb 2000

Dean? William Klein: Let me start by saying how much I enjoyed the paper by Dean et al. A good read.

Beta-Catenin and PS1

13 Aug 1999

signalling. I thought that we might open the forum with a brief discussion about why papers have demonstrated

Pin1, Tau and the Cell Cycle in Alzheimer Disease

03 Aug 1999

to submit additional comments by using our Comments form at the bottom of the page.   Paper under

In Search of γ-Secretase

• 5 Comments

05 May 1999

panelists with a remark? Otherwise, we'll go on.... Hardy: COMMENT The Nature paper reported

Apoptosis in Alzheimer Disease

24 Mar 1999

Perry: Is that what you said in your earlier papers? Carl Cotman: Yes Carl Cotman: Cummings- get back to

Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down's Syndrome Patients

28 May 1998

Leeuwen: Yes, we think. As indicated in the Science paper ref.30 we have found similar events outside the

Alzheimer Presenilins in the Nuclear Membrane, Interphase Kinetochores, and Centrosomes Suggest a Role in Chromosome Segregation

20 Mar 1998

comments by using our Comments form at the bottom of the page. Paper under Discussion: Li JH, Xu M, Zhou H.

Isolation of Single Immunohistochemically Identified Whole Neuronal Cell Bodies from Post-Mortem Human Brain for Simultaneous Anlaysis of Multiple Gene Expression

27 Feb 1998

additional comments by using our Comments form at the bottom of the page. Paper Under Discussion: Cheetham

Deficiency of Presenilin 1 Inhibits the Normal Cleavage of the Transmembrane Domain of Amyloid Precursor Protein

30 Jan 1998

to submit additional comments by using our Comments form at the bottom of the page. Paper Under