Clioquinol Trial Postmortem: Does Blocking Metal-Aβ Interactions Work?

15 Jan 2004

Neurology paper we reported that the side effects were not remarkable. Previously, clioquinol (CQ) was

Stem Cell Therapies for Neurodegenerative Disease: How Should We Push Ahead?

30 Mar 2004

Rao, are you as depressed as I am about those two Nature papers that just came out showing a failure of

Imaging in Alzheimer's Disease: The Current State of Affairs

27 Apr 2005

All, Higuchi et al. just published a paper on 19F and 1H MRI detection of amyloid-β plaques. Mikolaj

Differential Neuronal Vulnerability

• 2 Comments

29 Jun 2005

(mediated by gene expression differences as shown so well in this paper) to different insults. Once we

Weeding Mendel’s Garden: Can We Hoe Dubious Genetic Associations?

03 Aug 2012

original papers and understand enough to know whether you can trust it. Marc Cruts: I believe that it is

Cholesterol and Alzheimer's—Charging Fast But Still at a Distance from Solid Answers

• 3 Comments

19 Nov 2002

transport must be important. Gabrielle, check out the recent paper in Nature showing protection by statins

Calcium in AD Pathogenesis

• 5 Comments

09 Dec 2008

yes, Cell Calcium paper from De Smedt's group (see Kasri et al., 2006). Please see detailed

Gonadal Hormone Withdrawal, Apoptosis, and Generation of Beta Amyloid Peptide: A Vicious Cycle of Amyloidogenesis and Neurotoxicity in Alzheimer's Disease

• 5 Comments

05 Dec 2001

gonadotrophin levels under any circumstances. A paper on ovariectomy effects on Ab load in transgenic mice is in

β Amyloid Degradation: The Forgotten Half of Alzheimer's Disease

• 7 Comments

12 Sep 2002

thanks.. I was just looking at an older Selkoe paper concluding IDE mostly works extracellularly. Gabrielle

Alzheimer's: A Triple Whammy. Why are So Many Neurodegenerative Diseases Single, Double, or Triple Amyloidoses?

• 1 Comment

22 Oct 2003

Trojanowski If you look at recent work from Goedert and Crowther in PNAS, you will find their paper with

Sports Concussions, Dementia, and APOE Genotyping: What Can Scientists Tell the Public? What’s Up for Research?

• 3 Comments

09 Jun 2008

my slides, there's a citation to a recent paper in Acta Neuropath Scand about E4, falls without

Probing PPARγ? Agonists: Could Diabetes Drugs Treat Alzheimer's Disease?

• 1 Comment

16 Dec 2002

Gary Landreth The only data on BBB permeability is contained within a paper on pioglitazone published

Non-coding RNAs in Neurodegeneration

22 Oct 2007

Trinna Cuellar Joel, I agree with you. Some of the papers published in the last year or so demonstrating

Untapped Resource? New Study to Boost Acceptance of CSF Analysis

• 2 Comments

20 Sep 2010

LP, etc.)? A: This is published in the Nature Rev Neurol paper (see Blennow et al., 2010). Q: We are

Is Alzheimer’s Disease a Uniquely Human Disorder?

• 1 Comment

07 Dec 2016

be a reason that owners elect to euthanize (Fast et al., 2013). There is a new paper suggesting that