Are Glia Active Participants in Neurodegenerative Disease?

• 1 Comment

05 Dec 2005

Alzheimer’s and other neurodegenerative diseases. It has become trendy to say that glia are more than just

Cholinergic Plasticity in Hippocampus of Individuals with Mild Cognitive Impairment: Correlation with Alzheimer's Neuropathology

19 May 2003

in the Journal of Alzheimer's Disease, which is making the full text (.pdf) of these papers

From Here to There: AβPP as an Axonal Transport Receptor—How Could This Explain Neurodegeneration in AD?

15 Jul 2002

Alzheimer's, most Ab is degraded and does not accumulate. Larry Goldstein: Interesting. I'll have to

Mutations Impair TREM2 Maturation, Processing, and Microglial Phagocytosis

• 1 Comment

02 Jul 2014

TREM2 in the CSF of patients with Alzheimer’s and frontotemporal dementia. The mutations weakened

An Idiosyncratic View of AD Biomarkers

15 Jun 2006

Dr. Coleman led this live discussion on how biomarker information and basic science of AD can

Focus on the Locus! (Ceruleus, That Is, in Alzheimer’s Disease)

• 3 Comments

22 Dec 2010

hippocampus and cortex have grabbed the lion’s share of attention in Alzheimer’s disease, leaving other brain

Grasping the Shadow Force: Immune Cells in ALS

• 1 Comment

12 May 2011

Alzheimer’s disease. There, microglia cluster around amyloid-β plaques (Naert and Rivest, 2011). One and the

Protein Misfolding: An Unfolding Series of Discussions

09 Jun 2004

diseases? Maria Figueiredo Pereira I think that misfolded proteins are produced all the time and the

Reducing the Risk of Alzheimer Disease

23 Dec 2005

expressing familial Alzheimer disease (FAD)-linked amyloid-β precursor protein (APP) and presenilin (PS) that

Seeded Aggregation and Transmissible Proteopathy—Creepy Stuff Not Just for Prions Anymore?

• 7 Comments

30 Sep 2009

Alzheimer, Parkinson, and Huntington diseases, amyotrophic lateral sclerosis (ALS), and prion diseases, such

Whole Genome Study for Parkinson Disease

13 Dec 2006

Katrina Gwinn-Hardy led this Web seminar and discussion on the whole genome study of Parkinson

Role and Control of Metal-Mediated Fibril Toxicity

20 Dec 2004

David Allsop and Ashley Bush led this live discussion on 20 December 2004. Readers are invited to

Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down's Syndrome Patients

28 May 1998

protein and ubiquitin-B in Alzheimer's and Down's syndrome patients. Science 1998 Jan 9;279

Stress Granules and Neurodegenerative Disease—What’s the Scoop?

17 Feb 2011

sclerosis and frontotemporal lobar degeneration, where stress granule markers decorate pathological protein

Picking up the Pieces of Parkin

• 1 Comment

17 Jan 2002

Shai Shoham. Note: The transcript has been edited for clarity and accuracy. June: Hello and welcome