Webinar: The NeuronDB Knowledge Base

17 Oct 2006

this Webinar on 26 October 2006. Readers are invited to submit additional comments by using our

Early Detection of Alzheimer Disease—A Virtual Town Hall Meeting

• 1 Comment

09 Jul 2008

Reply by Douglas Galasko — Posted 26 July 2008 Confidence that early-stage AD patients indeed have AD is

Webinar: Cortex Aging Too Fast? Blame TMEM106B and Progranulin

10 Apr 2017

slowing down a person’s rate of biological aging—but how to find the requisite variants? In the April 26

Alzheimer's: A Triple Whammy. Why are So Many Neurodegenerative Diseases Single, Double, or Triple Amyloidoses?

• 1 Comment

22 Oct 2003

John Q. Trojanowski and Mark P. Mattson discussed the major commonality between many neurodegenerative diseases. Otherwise vastly different conditions that run the gamut from Alzheimer's, Parkinson's, Huntington's, ALS, to prion disorders,

Seeded Aggregation and Transmissible Proteopathy—Creepy Stuff Not Just for Prions Anymore?

• 7 Comments

30 Sep 2009

26;102(17):6098-102. Abstract Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E,

Slow Aβ; Clearance Is ApoE4’s Modus Operandi in Late-Onset AD

26 Jul 2011

David Holtzman — Posted 26 July 2011 Background Text by Gabrielle Strobel ApoE reigns supreme as the

Messing with the Membrane—An Alternative Interpretation of the Amyloid-β Hypothesis

• 20 Comments

01 Nov 2006

disease. Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9093-8. Copyright © 2005 National Academy of

Are Neurons Just Too Laissez-Faire about Repair?

• 1 Comment

24 Jul 2003

Thierry Nouspikel led this live discussion on 14 July 2003. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Dr. Thierry Nouspikel led this live discussion on 14 July 2003. Moderated by Dr

Ceramide and Cholesterol: Possible Connections Between Normal Aging of the Brain and Alzheimer’s Disease

15 Oct 2005

a long-chain (C26) ceramide synthase. A human homolog of LAG1 can correct the phenotype in yeast, so we do have

In Search of γ-Secretase

• 5 Comments

05 May 1999

Peter Nelson, with Dennis Selkoe, John Hardy, and Alain Israel, led this live discussion on 5 May 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion with Dennis Selkoe,

Alzheimer Immunotherapy Trial Grounded: Time to Reassess Safety and Vaccine Design

• 3 Comments

05 Mar 2002

Giulio Maria Pasinetti led this live discussion on 5 March 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.     Background Reading by Giulio Maria Pasinetti et al. (pdf file: download free Acrob

Grasping the Shadow Force: Immune Cells in ALS

• 1 Comment

12 May 2011

When two biological networks as complex as the nervous and immune systems cross paths, you know the interaction is not going to be simple. Add in neurodegeneration—such as amyotrophic lateral sclerosis—and it creates a web that will take many scientists t

How the Other Half Lives—Or the What, How, and Where of the AβPP Intracellular Domain

• 1 Comment

20 Sep 2002

Frank LaFerla led this live discussion on 20 September 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 20 September 2002, featuring Frank LaFerla of the Univers

Can We (Should We?) Develop “Smart Drugs” to Stave Off Age-Related Memory Loss?

• 3 Comments

13 Mar 2009

On 26 February 2009, we held a Webinar/Live Discussion with a slide presentation by Scott Small

How Does Excess Aβ Leave the Brain, How Does It Get In, And Can We Trap It Outside?

• 1 Comment

23 Jun 2003

Neurobiol Dis. 1997;4:27-34. Abstract 26. Poduslo JF, Curran GL. Amyloid-b peptide as a vaccine for