Generation of an Apoptotic Intracellular Peptide by γ-secretase Cleavage of Alzheimer's β-amyloid Precursor Protein

20 Sep 2000

cleavage of poly [ADR-ribose] polymerase (PARP) by cell death protease known as caspases (18) also

The Role of ApoE in Alzheimer's Disease: An Alternative View

11 Dec 2001

cultures. J Neurosci 18: 195-204. Abstract LaDu MJ, Falduto MT, Manelli AM, Reardon CA, Getz GS, Frail DE

Neural Stem Cells to the Rescue—Can Neuroreplacement Ever Become a Treatment for Alzheimer's?

09 Jul 2002

and recovery of cognitive function, Behavioral and Brain Sciences, 18 (1995) 10-35. 0 Tuesday, July 9,

RNAi in Neurodegenerative Diseases—What's the Therapeutic Potential?

18 Mar 2003

Medical School, Worcester, MA 01605 Zuoshang Xu led this live discussion on 18 March 2003. Readers are

Novel Substrates for BACE1 Beg the Question: What's the Biological Function of β-Secretase?

17 Dec 2003

limits amyloid beta-peptide production. J Biol Chem. 2002 Feb 15;277(7):5637-43. Abstract 18.

Clioquinol Trial Postmortem: Does Blocking Metal-Aβ Interactions Work?

15 Jan 2004

Chem. 2002 Oct 25;277(43):40302-8. Epub 2002 Aug 20. Abstract 18. Dong J, Atwood CS, Anderson VE,

Stem Cell Therapies for Neurodegenerative Disease: How Should We Push Ahead?

30 Mar 2004

2003 Nov;18(10):2707-12. Abstract Shors TJ, Townsend DA, Zhao M, Kozorovitskiy Y, Gould E. Neurogenesis

Vascular Factors in Alzheimer's Disease

21 Apr 2004

disease in the Rotterdam Study. Lancet. 1997 Jan 18;349(9046):151-4. Abstract Huang C, Wahlund LO,

Cast Call for Players: Healthy Aging Through Lean Living

17 Aug 2004

unpublished data where rats exposed to six months of leuprolide (a suppressor of leutinizing hormone) lived 18

Memantine: Implications for Treating Alzheimer's

29 Sep 2004

18 months, I believe (personal communication).     Dr. Kevin Foley How does a busy doctor in primary

Imaging in Alzheimer's Disease: The Current State of Affairs

27 Apr 2005

fluorine-18 (F-18) PIB compounds being used in human studies at Turku, Finland, and we are waiting to see

Now You See Them, Now You Don't: The Amyloid Channel Hypothesis

16 Jun 2005

Ever since amyloid-β (Aβ) was identified as the major component in amyloid plaques, scientists have been trying to decipher just exactly what the little peptide does. Most researchers would agree that Aβ is toxic to cells, but some are still skeptical. Ev

Whole Genome Study for Parkinson Disease

13 Dec 2006

Lancet Neurol. 2006 Nov ;5(11):911-6. Abstract Katrina Gwinn-Hardy led this live discussion on 18

The Functional Roles of APP Cytoplasmic Domain—Conflicts and Consensus

21 Dec 2006

Atlanta (Tuesday, October 18, 8:30 a.m.). Some of the items up for discussion will include the following:

Who Should Use the New Diagnostic Guidelines? The Debate Continues

13 Jan 2012

cortex on              [18]flurodeoxyglucose (FDG) positron emission tomography         c) atrophy on MRI