Therapeutics
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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
|---|---|---|---|---|---|---|
| Bemdaneprocel | BRT-DA01, MSK-DA01 |
Parkinson's Disease (Phase 1) | Bayer, BlueRock Therapeutics | Other Neurotransmitters, Other | Other | |
| Bryostatin 1 | Alzheimer's Disease (Phase 2) | Synaptogenix, Inc. | Other | Other | ||
| CDNF | cerebral dopamine neurotrophic factor | Parkinson's Disease (Phase 1/2) | Herantis Pharma Plc, Renishaw plc. | Other | Procedural Intervention, Other | |
| Cerebrolysin | Alzheimer's Disease (Phase 2) | Ebewe Pharmaceutical | Other | Other | ||
| CNM-Au8 | Gold nanocrystals | Parkinson's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Phase 2/3) | Clene Nanomedicine, Inc. | Metals, Other | Other | |
| Davunetide | NAP, AL-108 |
Mild Cognitive Impairment (Discontinued), Progressive Supranuclear Palsy (Discontinued), Schizophrenia (Discontinued), Frontotemporal Dementia (Inactive) | Allon Therapeutics Inc., Paladin Labs Inc. | Tau | Other | |
| DNL593 | PTV:PGRN, TAK-594 |
Frontotemporal Dementia (Phase 1/2) | Denali Therapeutics Inc., Takeda Pharmaceutical Company | Other | Other | |
| Estrogen | Premarin™ | Alzheimer's Disease (Discontinued) | Other | Other | Hormone Replacement Therapy | |
| GRF6019 | Alzheimer's Disease (Phase 2) | Alkahest, Inc., Grifols Biologicals Inc. | Inflammation, Other, Unknown | Other | ||
| GRF6021 | AKST/GRF6021 | Parkinson's Disease Dementia (Phase 2) | Alkahest, Inc., Grifols Biologicals Inc. | Inflammation, Other, Unknown | Other | |
| Intranasal oxytocin | Syntocinon, Pitocin |
Frontotemporal Dementia (Phase 2) | Other | Other | ||
| Leuprolide | Leuprolide acetate , Lupron Depot, Eligard |
Alzheimer's Disease (Phase 2) | Tolmar Pharmaceuticals, Inc. | Other | Other | Advanced prostate cancer |
| Liraglutide | Victoza™, Saxenda™ |
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 2) | Novo Nordisk A/S | Other | Other | Diabetes, weight loss |
| Lixisenatide | Adlyxin, Lyxumia |
Parkinson's Disease (Phase 2) | Sanofi | Other | Other | Type 2 diabetes |
| Lomecel-B | mesenchymal stem cells | Alzheimer's Disease (Phase 2) | Longeveron | Inflammation, Other | Other | |
| Low Dose Interleukin-2 | COYA-301, Aldesleukin, Proleukin, COYA-302, ld IL-2 |
Alzheimer's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Phase 3) | Coya Therapeutics | Inflammation | Other | |
| Nasal Insulin | Detemir, Levemir, Humulin, Novolin, glulisine |
Alzheimer's Disease (Phase 2/3), Mild Cognitive Impairment (Phase 2), Parkinson's Disease (Phase 2), Multiple System Atrophy (Phase 2) | Amyloid-Related, Other | Small Molecule, Other | Diabetes | |
| NurOwn™ | MSC-NTF Cells, debamestrocel , Neurotrophic factors-secreting Mesenchymal Stromal Cells |
Amyotrophic Lateral Sclerosis (Phase 3) | BrainStorm Cell Therapeutics, Inc. | Other | Other | |
| Sargramostim | GM-CSF Leukine , Leukine® |
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 1) | Genzyme, Partner Therapeutics, Inc., Sanofi | Inflammation, Other, Unknown | Other | Bone Marrow Stimulation |
| Semaglutide | Ozempic, Wegovy, Rybelsus |
Alzheimer's Disease (Phase 3), Parkinson's Disease (Phase 2) | Novo Nordisk A/S | Other | Other | Type 2 Diabetes, Obesity, Protection against myocardial infarction and stroke |
| Trappsol® Cyclo™ | HP-beta-CD, HPbetaCD |
Alzheimer's Disease (Phase 2) | Cyclo Therapeutics, Inc. | Cholesterol | Other | |
| Tricaprilin | AC-1204 , Caprylic triglyceride, AC-SD-03, CER-000, AC-OLE-O1-VA |
Alzheimer's Disease (Phase 3) | Cerecin Pte. Ltd. | Other | Supplement, Dietary, Other | None |
| Troriluzole | BHV-4157, trigriluzole, FC-4157 | Alzheimer's Disease (Discontinued) | Biohaven Pharmaceuticals | Other Neurotransmitters | Other | |
| XPro1595 | Pegipanermin, INB03, NeuLiv, XENP1595, DN-TNF, XENP345, XPro™ , LIVNate |
Alzheimer's Disease (Phase 2), Mild Cognitive Impairment (Phase 2) | INmune Bio Inc. | Inflammation | Other | |
| Young Plasma | Progressive Supranuclear Palsy (Inactive), Alzheimer's Disease (Inactive) | Alkahest, Inc., Grifols Biologicals Inc. | Inflammation, Other, Unknown | Other |