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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AL002 Alzheimer's Disease (Discontinued) AbbVie, Alector Inflammation Immunotherapy (passive)
AL003 Alzheimer's Disease (Discontinued) AbbVie, Alector Inflammation Immunotherapy (passive)
AL044 Alzheimer's Disease (Phase 1) Alector Inflammation Immunotherapy (passive)
DNL919 TAK-920,
ATV:TREM2
Alzheimer's Disease (Discontinued) Denali Therapeutics Inc., Takeda Pharmaceutical Company Amyloid-Related, Inflammation Immunotherapy (passive)
NT-0796 Propan-2-yl (2R)-2-{[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)- carbamoyl]oxy}-3-(pyrimidin-2-yl)propanoate Parkinson's Disease (Phase 1/2) NodThera Inflammation Small Molecule
TB006 Alzheimer's Disease (Phase 1) TrueBinding, Inc. Inflammation Immunotherapy (passive)
VG-3927 Alzheimer's Disease (Phase 1) Vigil Neuroscience, Inc. Amyloid-Related, Inflammation Small Molecule
VGL101 Iluzanebart Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (Phase 2) Vigil Neuroscience, Inc. Inflammation, Other Immunotherapy (passive)