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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
Aripiprazole Abilify,
BMS-337039
Alzheimer's Disease (Phase 3), Schizophrenia (Approved) Bristol-Myers Squibb, Otsuka Pharmaceutical Co., Ltd. Other Neurotransmitters Small Molecule
Citalopram escitalopram,
Celexa,
Lexapro ,
Cipralex
Alzheimer's Disease (Phase 3), Preclinical Alzheimer's Disease (Inactive) Other Neurotransmitters Small Molecule Depression, generalized anxiety disorder
Guanfacine Intuniv,
SPD503,
Afken,
Estulic,
Tenex
Alzheimer's Disease (Phase 3) Other Neurotransmitters Small Molecule Attention-deficit hyperactivity disorder, hypertension
Lumateperone ITI-007 Alzheimer's Disease (Phase 3), Schizophrenia (Phase 3), Bipolar Disorder (Phase 3) Bristol-Myers Squibb, Intra-Cellular Therapies, Inc. Other Neurotransmitters Small Molecule
Masupirdine SUVN-502 Alzheimer's Disease (Phase 3) Suven Life Sciences Ltd Other Neurotransmitters Small Molecule
Mirtazapine Remeron,
esmirtazapine,
Org 50081
Alzheimer's Disease (Phase 3) Other Neurotransmitters Small Molecule
Nabilone Cesamet Alzheimer's Disease (Phase 3), Parkinson's Disease (Phase 2) Bausch Health Companies Inc. Other Neurotransmitters Small Molecule Nausea associated with cancer chemotherapy (US and other countries); pain spasticity in multiple sclerosis (Canada and other countries).
Trazodone Trazodone hydrochloride,
Oleptro,
Desyrel
Alzheimer's Disease (Phase 3), Mild Cognitive Impairment (Phase 3), Amyotrophic Lateral Sclerosis (Phase 2/3) Other Neurotransmitters Small Molecule Depression