Therapeutics
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Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
---|---|---|---|---|---|---|
AL002 | Alzheimer's Disease (Phase 2) | AbbVie, Alector | Inflammation | Immunotherapy (passive) | ||
Baricitinib | Olumiant®, NCB28050, LY3009104 |
Alzheimer's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Phase 1) | Eli Lilly & Co. | Inflammation | Small Molecule | Rheumatoid arthritis, Eczema (Europe, Japan only) |
Benfotiamine | S-benzoylthiamine-O-monophosphate, Vitamin B1, Thiamine |
Alzheimer's Disease (Phase 2) | Inflammation, Other | Supplement, Dietary | ||
CY6463 | IW-6463 | Alzheimer's Disease (Phase 2) | Cyclerion | Inflammation | Small Molecule | |
Etanercept | Enbrel™ | Alzheimer's Disease (Phase 2) | Amgen, Inc., Pfizer | Inflammation | Immunotherapy (passive) | Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondilysis |
Foralumab | TZLS-401, NI-0401, 28F11-AE |
Alzheimer's Disease (Phase 2) | Tiziana Life Sciences | Inflammation | Immunotherapy (passive) | |
GRF6019 | Alzheimer's Disease (Phase 2) | Alkahest, Inc., Grifols Biologicals Inc. | Inflammation, Other, Unknown | Other | ||
Lenalidomide | Revlimid | Alzheimer's Disease (Phase 2) | Celgene Corporation | Amyloid-Related, Inflammation | Small Molecule | Multiple myeloma, lymphoma, myelodysplastic syndromes |
Lomecel-B | mesenchymal stem cells | Alzheimer's Disease (Phase 2) | Longeveron | Inflammation, Other | Other | |
Low Dose Interleukin-2 | COYA-301, Aldesleukin, Proleukin, COYA-302, ld IL-2 |
Alzheimer's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Phase 3) | Coya Therapeutics | Inflammation | Other | |
Montelukast | Singulair, MK0476 | Alzheimer's Disease (Phase 2) | Intelgenx | Inflammation | Small Molecule | Asthma |
MW150 | MW01-18-150SRM | Alzheimer's Disease (Phase 2) | Neurokine Therapeutics | Inflammation, Other | Small Molecule | |
Neflamapimod | VX-745 | Alzheimer's Disease (Phase 2), Dementia with Lewy Bodies (Phase 2), Huntington's Disease (Discontinued) | CervoMed, Inc. | Inflammation | Small Molecule | |
Sargramostim | GM-CSF Leukine , Leukine® |
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 1) | Genzyme, Partner Therapeutics, Inc., Sanofi | Inflammation, Other, Unknown | Other | Bone Marrow Stimulation |
XPro1595 | Pegipanermin, INB03, NeuLiv, XENP1595, DN-TNF, XENP345, XPro™ , LIVNate |
Alzheimer's Disease (Phase 2), Mild Cognitive Impairment (Phase 2) | INmune Bio Inc. | Inflammation | Other |