Therapeutics
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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
|---|---|---|---|---|---|---|
| Aduhelm | Aducanumab, BIIB037 |
Alzheimer's Disease (Approved) | Biogen, Neurimmune | Amyloid-Related | Immunotherapy (passive) | |
| Brexpiprazole | Rexulti, OPC 34712 |
Alzheimer's Disease (Approved), Schizophrenia (Approved) | Lundbeck, Otsuka Pharmaceutical Co., Ltd. | Other Neurotransmitters | Small Molecule | |
| Donanemab | N3pG-Aβ Monoclonal Antibody, LY3002813, Kisunla |
Alzheimer's Disease (Approved) | Eli Lilly & Co. | Amyloid-Related | Immunotherapy (passive) | |
| Donepezil | Aricept™, Donepezil hydrochloride, Eranz®, E 2020 |
Alzheimer's Disease (Approved), Dementia with Lewy Bodies (Inactive), Down's Syndrome (Inactive), Parkinson's Disease Dementia (Inactive) | Corium, Inc., Eisai Co., Ltd., Pfizer | Cholinergic System | Small Molecule | Alzheimer's Disease, Dementia with Lewy Bodies (Japan) |
| Galantamine | Razadyne™, Reminyl™, Nivalin® |
Alzheimer's Disease (Approved) | Janssen, Ortho-McNeil Pharmaceutical, Sanochemia Pharmazeutika, Shire, Takeda Pharmaceutical Company | Cholinergic System | Small Molecule | Mild to Moderate Alzheimer's disease |
| Leqembi | Lecanemab-irmb, BAN2401, mAb158 |
Alzheimer's Disease (Approved) | BioArctic AB, Biogen, Eisai Co., Ltd. | Amyloid-Related | Immunotherapy (passive) | |
| Memantine | Ebixa™, Namenda™ , Axura®, Akatinol®, Memary® |
Alzheimer's Disease (Approved) | Forest Laboratories, Inc., Lundbeck, Merz Pharma | Other Neurotransmitters | Small Molecule | Alzheimer's Disease |
| Rivastigmine | Exelon™, Rivastigmine tartrate , Rivastach® Patch, Prometax®, SDZ ENA 713 |
Alzheimer's Disease (Approved), Parkinson's Disease Dementia (Approved) | Novartis Pharmaceuticals Corporation | Cholinergic System | Small Molecule | Mild to moderate Alzheimer’s disease and mild to moderate dementia related to Parkinson's disease |
| Suvorexant | Belsomra, MK-4305 |
Alzheimer's Disease (Approved) | Merck | Other | Small Molecule | Insomnia, Insomnia in mild to moderate Alzheimer's disease |
| Tacrine | Cognex™ | Alzheimer's Disease (Approved) | Pfizer, Shionogi Pharma | Cholinergic System | Small Molecule |