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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
Bemdaneprocel BRT-DA01,
MSK-DA01
Parkinson's Disease (Phase 1) Bayer, BlueRock Therapeutics Other Neurotransmitters, Other Other
Bryostatin 1 Alzheimer's Disease (Phase 2) Synaptogenix, Inc. Other Other
CDNF cerebral dopamine neurotrophic factor Parkinson's Disease (Phase 1/2) Herantis Pharma Plc, Renishaw plc. Other Procedural Intervention, Other
Cerebrolysin Alzheimer's Disease (Phase 2) Ebewe Pharmaceutical Other Other
CNM-Au8 Gold nanocrystals Parkinson's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Phase 2/3) Clene Nanomedicine, Inc. Metals, Other Other
Davunetide NAP,
AL-108
Mild Cognitive Impairment (Discontinued), Progressive Supranuclear Palsy (Discontinued), Schizophrenia (Discontinued), Frontotemporal Dementia (Inactive) Allon Therapeutics Inc., Paladin Labs Inc. Tau Other
DNL593 PTV:PGRN,
TAK-594
Frontotemporal Dementia (Phase 1/2) Denali Therapeutics Inc., Takeda Pharmaceutical Company Other Other
Estrogen Premarin™ Alzheimer's Disease (Discontinued) Other Other Hormone Replacement Therapy
GRF6019 Alzheimer's Disease (Phase 2) Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other
GRF6021 AKST/GRF6021 Parkinson's Disease Dementia (Phase 2) Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other
Intranasal oxytocin Syntocinon,
Pitocin
Frontotemporal Dementia (Phase 2) Other Other
Leuprolide Leuprolide acetate ,
Lupron Depot,
Eligard
Alzheimer's Disease (Phase 2) Tolmar Pharmaceuticals, Inc. Other Other Advanced prostate cancer
Liraglutide Victoza™,
Saxenda™
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 2) Novo Nordisk A/S Other Other Diabetes, weight loss
Lixisenatide Adlyxin,
Lyxumia
Parkinson's Disease (Phase 2) Sanofi Other Other Type 2 diabetes
Lomecel-B mesenchymal stem cells Alzheimer's Disease (Phase 2) Longeveron Inflammation, Other Other
Low Dose Interleukin-2 COYA-301,
Aldesleukin,
Proleukin,
COYA-302,
ld IL-2
Alzheimer's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Phase 3) Coya Therapeutics Inflammation Other
Nasal Insulin Detemir,
Levemir,
Humulin,
Novolin,
glulisine
Alzheimer's Disease (Phase 2/3), Mild Cognitive Impairment (Phase 2), Parkinson's Disease (Phase 2), Multiple System Atrophy (Phase 2) Amyloid-Related, Other Small Molecule, Other Diabetes
NurOwn™ MSC-NTF Cells,
debamestrocel ,
Neurotrophic factors-secreting Mesenchymal Stromal Cells
Amyotrophic Lateral Sclerosis (Phase 3) BrainStorm Cell Therapeutics, Inc. Other Other
Sargramostim GM-CSF Leukine ,
Leukine®
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 1) Genzyme, Partner Therapeutics, Inc., Sanofi Inflammation, Other, Unknown Other Bone Marrow Stimulation
Semaglutide Ozempic,
Wegovy,
Rybelsus
Alzheimer's Disease (Phase 3), Parkinson's Disease (Phase 2) Novo Nordisk A/S Other Other Type 2 Diabetes, Obesity, Protection against myocardial infarction and stroke
Trappsol® Cyclo™ HP-beta-CD,
HPbetaCD
Alzheimer's Disease (Phase 2) Cyclo Therapeutics, Inc. Cholesterol Other
Tricaprilin AC-1204 ,
Caprylic triglyceride,
AC-SD-03,
CER-000,
AC-OLE-O1-VA
Alzheimer's Disease (Phase 3) Cerecin Pte. Ltd. Other Supplement, Dietary, Other None
Troriluzole BHV-4157, trigriluzole, FC-4157 Alzheimer's Disease (Discontinued) Biohaven Pharmaceuticals Other Neurotransmitters Other
XPro1595 Pegipanermin, INB03, NeuLiv, XENP1595, DN-TNF, XENP345,
XPro™ ,
LIVNate
Alzheimer's Disease (Phase 2), Mild Cognitive Impairment (Phase 2) INmune Bio Inc. Inflammation Other
Young Plasma Progressive Supranuclear Palsy (Inactive), Alzheimer's Disease (Inactive) Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other