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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
|---|---|---|---|---|---|---|
| AL003 | Alzheimer's Disease (Discontinued) | AbbVie, Alector | Inflammation | Immunotherapy (passive) | ||
| Azeliragon | PF-04494700, TTP488 |
Alzheimer's Disease (Discontinued) | Pfizer, TransTech Pharma, Inc., vTv Therapeutics LLC | Amyloid-Related, Inflammation | Small Molecule | |
| Celecoxib | Celebrex | Alzheimer's Disease (Discontinued) | Pfizer | Inflammation | Small Molecule | Pain, Arthritis |
| DNL919 | TAK-920, ATV:TREM2 |
Alzheimer's Disease (Discontinued) | Denali Therapeutics Inc., Takeda Pharmaceutical Company | Amyloid-Related, Inflammation | Immunotherapy (passive) | |
| Gammagard® | Intravenous Immunoglobulin, IVIg |
Alzheimer's Disease (Discontinued) | Baxter Healthcare | Amyloid-Related, Inflammation | Immunotherapy (passive) | Immunodeficiency conditions |
| HF0220 | Alzheimer's Disease (Discontinued) | Newron | Inflammation | Small Molecule | ||
| Ibuprofen | Advil™, Nuprin™ , Motrin™ |
Alzheimer's Disease (Discontinued) | Amyloid-Related, Inflammation | Small Molecule | Pain and Fever | |
| Inzomelid | Emlenoflast, IZD174, MCC-7840 |
Alzheimer's Disease (Discontinued), Parkinson's Disease (Discontinued) | Hoffmann-La Roche, Inflazome Ltd. | Inflammation | Small Molecule | |
| Lornoxicam | Alzheimer's Disease (Discontinued), Mild Cognitive Impairment (Discontinued) | JSW Lifesciences | Inflammation | Small Molecule | Pain in US | |
| Naproxen | Aleve™, Anaprox™, Naprosyn™ |
Alzheimer's Disease (Discontinued) | Procter & Gamble | Inflammation | Small Molecule | Over-the-counter drug for reduction of pain, fever, inflammation, and stiffness. |
| Prednisone | Alzheimer's Disease (Discontinued) | Inflammation | Small Molecule | |||
| Rofecoxib | Vioxx™ | Alzheimer's Disease (Discontinued) | Merck | Inflammation | Small Molecule | Withdrawn from market |
| Thalidomide | Thalomid® | Alzheimer's Disease (Discontinued) | Celgene Corporation | Amyloid-Related, Inflammation | Small Molecule | |
| Varoglutamstat | PQ912 | Alzheimer's Disease (Discontinued) | Probiodrug AG, Vivoryon Therapeutics N.V. | Amyloid-Related, Inflammation | Small Molecule |