Therapeutics
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Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
---|---|---|---|---|---|---|
ABT-089 | Alzheimer's Disease (Discontinued) | Abbott Laboratories | Cholinergic System | Small Molecule | ||
ABT-288 | Alzheimer's Disease (Discontinued) | AbbVie | Cholinergic System, Other Neurotransmitters | Small Molecule | ||
ABT 418 | Alzheimer's Disease (Discontinued) | Cholinergic System | Small Molecule | None | ||
AF 102B | cevimeline HCL, Evoxac™ |
Alzheimer's Disease (Discontinued) | SnowBrand Pharmaceuticals, Inc. | Cholinergic System | Small Molecule | Treatment of dry mouth in Sjogren's syndrome. |
AZD1446 | TC-6683 | Alzheimer's Disease (Discontinued) | AstraZeneca, Targacept | Cholinergic System | Small Molecule | None |
Encenicline | EVP-6124 , MT-4666, α7-nAChR agonist |
Alzheimer's Disease (Discontinued), Schizophrenia (Discontinued) | FORUM Pharmaceuticals Inc., Mitsubishi Tanabe Pharma | Cholinergic System | Small Molecule | None |
Eptastigmine | MF 201 | Alzheimer's Disease (Discontinued) | Mediolanum | Cholinergic System | Small Molecule | None |
GSK239512 | Alzheimer's Disease (Discontinued) | GlaxoSmithKline (GSK) | Cholinergic System, Other Neurotransmitters | Small Molecule | ||
Ladostigil | Ladostigil hemitartrate, TV3326 |
Mild Cognitive Impairment (Phase 2), Alzheimer's Disease (Discontinued) | Avraham Pharmaceuticals Ltd | Cholinergic System | Small Molecule | |
LU25-109 | Alzheimer's Disease (Discontinued) | Cholinergic System | Small Molecule | None | ||
Metrifonate | trichlorfon | Alzheimer's Disease (Discontinued) | Cholinergic System | Small Molecule | None | |
Milameline | CI 979 | Alzheimer's Disease (Discontinued) | Aventis Pharmaceuticals, Inc. (was Hoechst) | Cholinergic System | Small Molecule | None |
Nefiracetam | Alzheimer's Disease (Discontinued) | Daiichi Sankyo Pharmaceuticals | Cholinergic System | Small Molecule | None | |
Nelonicline | ABT-126 | Alzheimer's Disease (Discontinued), Schizophrenia (Inactive) | AbbVie | Cholinergic System | Small Molecule | |
PF-06852231 | Alzheimer's Disease (Discontinued) | Pfizer | Cholinergic System | Small Molecule | ||
Physostigmine Salicylate | Synapton | Alzheimer's Disease (Discontinued) | Forest Laboratories, Inc. | Cholinergic System | Small Molecule | |
S 38093 | Alzheimer's Disease (Discontinued) | Servier | Cholinergic System, Other Neurotransmitters | Small Molecule | ||
Varenicline | Champix™, Chantix™, Varenicline tartrate, CP-526,555, Alpha4 beta2 nicotinic receptor agonist |
Alzheimer's Disease (Discontinued) | Pfizer | Cholinergic System | Small Molecule | Smoking cessation |