Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R, . Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. 2013 Apr 10;309(14):1483-92. PubMed.

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News

  1. AD GWAS in African Americans Confirms, Reshuffles AlzGene List
  2. Late-Onset Disease Clusters in Families with Alzheimer’s
  3. Largest Alzheimer GWAS in African Americans Finds New Variants

Mutations

  1. APOE c.-647A>G (rs439382)
  2. APOE R176C (ApoE2)
  3. APOE c.-558A>T (rs449647)
  4. APOE c.-286T>G (rs405509)
  5. APOE c.43+78G>A (rs769449)
  6. APOE c.43+520G>A (rs769450)